TAILORx Tissue Bank

Breast Cancer Bank of Tissue From Trial Assigning Individualized Options for Treatment (TAILORx Tissue Bank)

This is an exploratory, translational, non-interventional and multi-centre biobank. The aim of the development of such a biobank is to identify potential biomarkers that are indicative of disease relapse.

The primary objective is to develop a biobank, tissue microarrays (TMAs) and full face sections, which will be used to identify candidate/ novel biomarkers prognostic for disease relapse and predictive for endocrine and/or chemotherapy resistance.

The secondary objectives are:

• To validate emerging signatures/biomarkers identified.
• To develop new assays for the breast cancer clinic.

Inclusion Criteria:

• Patients that were registered with the ICORG 06-31 TAILORx trial and participated in trial arms
• Patients with adequate tumor tissue available