Data will be collected for commercially available Sponsor devices. These systems treat both the humeral and glenoid side of the shoulder joint. The following products will be included in the study in the geographies where they are commercially available.

• Aequalis Ascend Flex Convertible Shoulder System
• Pyrocarbon Humeral Head (used with Aequalis Ascend Flex)
• Simpliciti Shoulder Prosthesis
• Aequalis Reversed Fracture Prosthesis
• Aequalis PerFORM Glenoid
• Aequalis PerFORM+ Glenoid
• Aequalis PerFORM Reversed Glenoid

Devices previously included, but discontinued under clinical investigation plan (CIP) version 4.0:

• Aequalis Resurfacing Head
• Aequalis Ascend Anatomic Shoulder System
• Aequalis IM Humeral Nail - Short and Long
• ORTHOLOC™ SPS (Shoulder Plating System)
• Aequalis Reversed II Shoulder System
• Aequalis Adjustable Reversed Prosthesis
• Aequalis Flex Revive Shoulder System

Adverse events will be evaluated from inclusion to last follow-up and will be documented during the study and categorized as whether they are serious and whether they are related to the Sponsor device or implant procedure.

The cumulative incidence of device revisions and reoperations will be reported as well as Kaplan-Meier estimates for implant survival at the end of the clinical investigation.

Time from primary study surgery to revision surgery

ASES Score = American Shoulder and Elbow Surgeons Score