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To determine the short term therapeutic efficacies of Gufoni maneuver and mastoid oscillation in apogeotropic type of benign paroxysmal positional vertigo (BPPV) involving the horizontal semicircular canal (HC-BPPV), a randomized, prospective, sham-controlled study was conducted.
The apogeotropic type of benign paroxysmal positional vertigo involving the horizontal canal (HC-BPPV) is likely due to otolithic debris in the anterior arm of the canal (canalithiasis) or the debris attached to the cupula (cupulolithiasis). It is important to seek the method to convert treatment-resistant apogeotropic form to the more treatment-responsive geotropic form in HC-BPPV. Recent randomized trials demonstrated that head shaking maneuver was more effective than the modified Semont maneuver and the Gufoni and head shaking maneuvers showed similar efficacy in treating apogeotropic HC-BPPV. Moreover, new repositioning maneuver using mastoid vibration showed good efficacies in patients with apogeotropic HC-BPPV in recent study. So we tried to compare the short term therapeutic efficacies of Gufoni maneuver and mastoid oscillation in apogeotropic HC-BPPV with a randomized, prospective, sham-controlled study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gufoni | Experimental | Gufoni maneuver for apogeotropic horizontal BPPV at the first day |
|
| Vibration | Experimental | Vibration maneuver for apogeotropic horizontal BPPV at the first day |
|
| Sham | Sham Comparator | Sham maneuver for apogeotropic horizontal BPPV at the first day |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Gufoni | Procedure |
| ||
| Vibration |
| Measure | Description | Time Frame |
|---|---|---|
| Conversion in Direction of Nystagmus From Apogeotropic to Geotropic or Disappearance of Nystagmus | 2 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hyun Ah Kim | Daegu KyungBook Dizziness society | Study Director |
| Hyung Lee | Keimyung University Dongsan Medical Centerl | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Daegu Kyungbook Dizziness society | Daegu | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28220291 | Derived | Kim HA, Park SW, Kim J, Kang BG, Lee J, Han BI, Seok JI, Chung EJ, Kim J, Lee H. Efficacy of mastoid oscillation and the Gufoni maneuver for treating apogeotropic horizontal benign positional vertigo: a randomized controlled study. J Neurol. 2017 May;264(5):848-855. doi: 10.1007/s00415-017-8422-2. Epub 2017 Feb 20. |
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217 patients enrolled in the study but 8 retracted their agreements.
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| ID | Title | Description |
|---|---|---|
| FG000 | Gufoni | Gufoni maneuver for apogeotropic horizontal benign paroxysmal positional vertigo (BPPV) at the first day Gufoni |
| FG001 | Vibration | Vibration maneuver for apogeotropic horizontal BPPV at the first day Vibration |
| FG002 | Sham | Sham maneuver for apogeotropic horizontal BPPV at the first day Sham |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
217 patients enrolled in the study but 8 retracted their agreements.
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| ID | Title | Description |
|---|---|---|
| BG000 | Gufoni | Gufoni maneuver for apogeotropic horizontal BPPV at the first day Gufoni |
| BG001 | Vibration | Vibration maneuver for apogeotropic horizontal BPPV at the first day Vibration |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Conversion in Direction of Nystagmus From Apogeotropic to Geotropic or Disappearance of Nystagmus | 217 patients enrolled in the study but 8 retracted their agreements. | Posted | Number | participants | 2 days |
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Gufoni | Gufoni maneuver for apogeotropic horizontal BPPV at the first day Gufoni |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Dr. Hyun Ah Kim | Daegu Kyungbook Dizziness society | +82-53-250-7475 | kha0206@dsmc.or.kr |
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| ID | Term |
|---|---|
| D065635 | Benign Paroxysmal Positional Vertigo |
| ID | Term |
|---|---|
| D014717 | Vertigo |
| D015837 | Vestibular Diseases |
| D007759 | Labyrinth Diseases |
| D004427 | Ear Diseases |
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| ID | Term |
|---|---|
| D014732 | Vibration |
| C005703 | salicylhydroxamic acid |
| ID | Term |
|---|---|
| D055595 | Mechanical Phenomena |
| D055585 | Physical Phenomena |
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|
| Sham | Procedure |
|
| BG002 | Sham | Sham maneuver for apogeotropic horizontal BPPV at the first day Sham |
| BG003 | Total | Total of all reporting groups |
| years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Symptom duration | Mean | Full Range | days |
|
| Lesion side | Number | participants |
|
|
|
|
| 0 |
| 72 |
| 0 |
| 72 |
| EG001 | Vibration | Vibration maneuver for apogeotropic horizontal BPPV at the first day Vibration | 0 | 72 | 0 | 72 |
| EG002 | Sham | Sham maneuver for apogeotropic horizontal BPPV at the first day Sham | 0 | 73 | 0 | 73 |
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| D010038 |
| Otorhinolaryngologic Diseases |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |