A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

This is a randomized trial comparing oxytocin versus oxytocin + syntometrine in the prevention of post partum haemorrhage in patients undergoing caesarean section

Inclusion Criteria:

• Pregnant women delivering by caesarean section older than 18 years willing and able to give informed consent

Exclusion Criteria:

• • Women not willing or women not able to provide consent

  • Women who have a classical caesarean section
  • Women younger than 18 years of age
  • Women with any of the following conditions will be excluded (ergometrine contra-indicated in patients with these conditions).
  • Pre- eclampsia
  • Eclampsia,
  • Uncontrolled hypertension (hypertension defined as systolic blood pressure more than 140 mm Hg and diastolic blood pressure more than 90 mm Hg)
  • Any cardiac lesion
  • Impaired liver function
  • Impaired kidney function
  • Hypersensitivity to any of the active ingredients of the preparations that will be used (Syntometrine® or Syntocinon®)
  • Occlusive vascular disease
  • Autoimmune vasculitis