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In Sub-Saharan Africa (SSA), many children die from diarrhoea, acute respiratory illness (ARI) and malaria, despite well- recognized, inexpensive and highly effective treatments, since health access and human resources are limited. Healthy Child Uganda (HCU) is a Ugandan-Canadian partnership that since 2003, has developed, implemented and evaluated a Village Health Volunteer (VHV) program in 175 rural villages. Volunteers, selected by peers, provide health education and refer sick children. Volunteer retention (94%) and significant decreases in child deaths are remarkable. Now, HCU wonders whether VHV scope can extend to provide treatment for sick children using Oral Rehydration Salts (ORS)/Zinc, antibiotics, and antimalarials. Use of lay providers in this capacity, called integrated community case management (iCCM), has been proposed as a potential inexpensive solution to SSA's human health resource crisis.
PRIMARY QUESTION: In rural southwest Uganda, can iCCM provided by lay volunteers, improve the proportion of children with diarrhoea receiving ORS/Zn, ARI receiving antibiotics, and fever/malaria receiving antimalarials? Secondary study questions consider VHV capacity to prescribe appropriate drug, dose, duration; iCCM acceptance by family, and VHV; VHV retention/motivation; program cost. Selected VHV will be iCCM trained then receive treatments for distribution. Qualitative and quantitative methods including household surveys, and focus groups will consider pre/post intervention differences and differences in control and intervention populations. A research short course and micro research grants (~ $3000 to multidisciplinary groups pursuing relevant questions) will promote health system evaluation capacity. Lessons learned are critical as SSA countries move forward in planning for increased iCCM programming.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICCM delivered by VHT | Active Comparator | Health Outcomes in Communities where VHT's were trained in ICCM and given drugs. |
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| ICCM delivered by VHT with cell phone | Active Comparator | Health Outcomes in communities with VHT's who were trained in ICCM and given cell phones |
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| Health outcomes in communities with no ICCM | Active Comparator | Health outcomes in communities with VHT's who were not trained in ICCM |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ICCM delivered by VHT | Other | VHT's deliver ICCM to children under five in their communities |
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| Measure | Description | Time Frame |
|---|---|---|
| Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for presumed pneumonia. | Children diagnosed by a Community Health Worker with presumed pneumonia (fast breathing and cough) treated with Amoxicillin. | March 2013 - November 2014 (8 months) |
| Percentage of change in number of children under five in intervention area who receive appropriate Integrated Community Case Management Treatment from a Community Health Worker for diarrhea | Children diagnosed with diarrhea will be treated with ORS and zinc. | March 2013 - November 2014 (8 months) |
| Percentage of change in number of children under five in intervention area who receive Integrated Community Case Management Treatment from a Community Health Worker for fever. | Children diagnosed with fever are presumed to have malaria, as per government treatment guidelines, and are treated with Coartem. | March 2013 - November 2014 (8 months) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Samuel Maling | MUST | Principal Investigator |
| Celestine Barigye | MUST | Principal Investigator |
| Jerome Kabakyenga | MUST | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33565123 | Derived | Oliphant NP, Manda S, Daniels K, Odendaal WA, Besada D, Kinney M, White Johansson E, Doherty T. Integrated community case management of childhood illness in low- and middle-income countries. Cochrane Database Syst Rev. 2021 Feb 10;2(2):CD012882. doi: 10.1002/14651858.CD012882.pub2. |
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| ICCM delivered by VHT with Cell Phone | Other | ICCM delivered to children under 5 by VHT trained in ICCM and given cell phones |
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| No intervention | Other | VHT's selected by no ICCM training given and no drugs or cell phones. |
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