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| Name | Class |
|---|---|
| Deutsche Morbus Crohn / Colitis ulcerosa Vereinigung DCCV | UNKNOWN |
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The aim of this randomized trial is to investigate the effects of a 12-week yoga intervention compared to self-care on quality of life, stress, psychological health, and physiological parameters in 77 patients with ulcerative colitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Yoga | Experimental |
| |
| Self-care | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Yoga | Behavioral | 12-week Hatha Yoga intervention 90 minutes once a week |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Disease-specific quality of life | Inflammatory Bowel Disease Questionnaire (IBDQ) | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Disease-specific quality of life | Inflammatory Bowel Disease Questionnaire (IBDQ) | 6 months |
| Generic quality of life | 36-Item Short Form Health Survey (SF-36) |
| Measure | Description | Time Frame |
|---|---|---|
| Adherence | Intervention adherence (number of sessions attended and home practice diary) | 3 months |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Holger Cramer, PhD | Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany | Principal Investigator |
| Jost Langhorst, MD | Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen | Essen | 45276 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40243391 | Derived | Tiles-Sar N, Neuser J, de Sordi D, Baltes A, Preiss JC, Moser G, Timmer A. Psychological interventions for treatment of inflammatory bowel disease. Cochrane Database Syst Rev. 2025 Apr 17;4(4):CD006913. doi: 10.1002/14651858.CD006913.pub3. | |
| 31927346 | Derived | Koch AK, Schols M, Langhorst J, Dobos G, Cramer H. Perceived stress mediates the effect of yoga on quality of life and disease activity in ulcerative colitis. Secondary analysis of a randomized controlled trial. J Psychosom Res. 2020 Mar;130:109917. doi: 10.1016/j.jpsychores.2019.109917. Epub 2019 Dec 31. |
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| ID | Term |
|---|---|
| D003093 | Colitis, Ulcerative |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| ID | Term |
|---|---|
| D015013 | Yoga |
| D012648 | Self Care |
| ID | Term |
|---|---|
| D026441 | Mind-Body Therapies |
| D000529 | Complementary Therapies |
| D013812 | Therapeutics |
| D026443 | Spiritual Therapies |
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| Self-care |
| Behavioral |
Self-care books are provided for self-directed use |
|
|
| 3 months |
| Generic quality of life | 36-Item Short Form Health Survey (SF-36) | 6 months |
| Anxiety/depression | Hospital Anxiety and Depresion Scale (HADS) | 3 months |
| Anxiety/depression | Hospital Anxiety and Depresion Scale (HADS) | 6 months |
| Subjective stress | Perceived Stress Scale (PSS) | 3 months |
| Subjective stress | Perceived Stress Scale (PSS) | 6 months |
| Subjective stress | Perceived Stress Questionnaire (PSQ) | 3 months |
| Subjective stress | Perceived Stress Questionnaire (PSQ) | 6 months |
| Positive/negative affect | Positive and Negative Affect Schedule (PANAS) | 3 months |
| Positive/negative affect | Positive and Negative Affect Schedule (PANAS) | 6 months |
| Body awareness | Body Awareness Questionnaire (BAQ) | 3 months |
| Body awareness | Body Awareness Questionnaire (BAQ) | 6 months |
| Body responsiveness | Body Responsiveness Scale (BRS) | 3 months |
| Body responsiveness | Body Responsiveness Scale (BRS) | 6 months |
| Self-efficacy | General Self-Efficacy Scale | 3 months |
| Self-efficacy | General Self-Efficacy Scale | 6 months |
| C-reactive protein | C-reactive protein | 3 months |
| C-reactive protein | C-reactive protein | 6 months |
| Blood sedimentation rate | Blood sedimentation rate | 3 months |
| Blood sedimentation rate | Blood sedimentation rate | 6 months |
| Faecal calprotectin | Faecal calprotectin | 3 months |
| Faecal calprotectin | Faecal calprotectin | 6 months |
| Faecal lactoferrin | Faecal lactoferrin | 3 months |
| Faecal lactoferrin | Faecal lactoferrin | 6 months |
| Faecel PMN-elastase | Faecel PMN-elastase | 3 months |
| Faecel PMN-elastase | Faecel PMN-elastase | 6 months |
| Disease activity | Clinical Activity Index (CAI-Rachmilewitz) | 3 months |
| Disease activity | Clinical Activity Index (CAI-Rachmilewitz) | 6 months |
| Salivary cortisol level | Salivary cortisol level - cortisol awakening response | 3 months |
| Steroid sensitivity | Steroid sensitivity (IC50) | 3 months |
| Andrenergic sensitivity | Andrenergic sensitivity (IC50) | 3 months |
| Cholinergic sensitivity | Cholinergic sensitivity (IC50) | 3 months |
| Safety | Number of patients with adverse events/serious adverse events | 3 months |
| Safety | Number of patients with adverse events/serious adverse events | 6 months |
| Hemogram | Hemogram | 3 months |
| Hemogram | Hemogram | 6 months |
| 28378342 | Derived | Cramer H, Schafer M, Schols M, Kocke J, Elsenbruch S, Lauche R, Engler H, Dobos G, Langhorst J. Randomised clinical trial: yoga vs written self-care advice for ulcerative colitis. Aliment Pharmacol Ther. 2017 Jun;45(11):1379-1389. doi: 10.1111/apt.14062. Epub 2017 Apr 5. |
| D015212 |
| Inflammatory Bowel Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D026241 |
| Exercise Movement Techniques |
| D026741 | Physical Therapy Modalities |
| D012046 | Rehabilitation |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |