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pain control in pediatric renal transplant is a major concern. the main goal during anesthesia of renal transplant in pediatrics is to maintain hemodynamics in a range close to that of the adult donor. epidural analgesia is thought to be very effective in pain control. this study emphasises the ease of application of epidural catheter via the caudal route to the lower thoracic level; avoiding possible complications that may arise from lumbar or thoracic routes, and its effects on hemodynamics when using analgesic doses of local anesthetics and narcotics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| caudal epidural catheterization group | Active Comparator | 30 patients received continuous intra and post-operative caudal epidural infusion of bupivacaine 0.125% with fentanyl (2 microgram/ml) over 24 hours |
|
| control group | Sham Comparator | 30 patients didn't receive caudal epidural analgesia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| B-Braun, Perifix® ONE Paed, Germany | Device | caudal epidural catheterization bupivacaine fentanyl |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intraoperative blood pressure | measure systolic and diastolic blood pressure | from the induction of anesthesia till end of surgery at half an hour intervals |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative blood pressure | record systolic and diastolic blood pressure every hour for the first 24 hours postoperative | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours |
| intraoperative central venous pressure |
| Measure | Description | Time Frame |
|---|---|---|
| pain scoring system (objective behavioural pain score) | from the time of transfere to the nephrology ICU, every hour for the first 24 hours postoperative |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sherif M Soaida, M.D. | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of medicine, Cairo University | Cairo | 11562 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26493396 | Derived | Soaida SM, ElSheemy MS, Shouman AM, Shoukry AI, Morsi HA, Salah DM, Fadel FI, Bazaraa HM. Caudal extradural catheterization in pediatric renal transplant and its effect on perioperative hemodynamics and pain scoring: a prospective randomized study. J Anesth. 2016 Feb;30(1):47-54. doi: 10.1007/s00540-015-2087-8. Epub 2015 Oct 22. |
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| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| ID | Term |
|---|---|
| D008614 | Meperidine |
| D015742 | Propofol |
| D002045 | Bupivacaine |
| D005283 | Fentanyl |
| ID | Term |
|---|---|
| D007540 | Isonipecotic Acids |
| D000147 | Acids, Heterocyclic |
| D006571 | Heterocyclic Compounds |
| D010880 | Piperidines |
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| Pethidine | Drug | pethidine intravenous at a dose 1mg/kg when pain score more than 5 postoperative rescue analgesia |
|
| Propofol | Drug | fentanyl propofol atracurium besylate |
|
| Bupivacaine | Drug |
|
| Fentanyl | Drug |
|
| fromom the induction of anesthesia till end of surgery at half an hour intervals |
| postoperative heart rate | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours |
| postoperative central venous pressure | from the time of transfer of the patient to the intensive care unit at one hour intervals for 24 hours |
| intraoperative heart rate | from the induction of anesthesia till end of surgery at half an hour intervals |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D006573 |
| Heterocyclic Compounds, 1-Ring |
| D010636 | Phenols |
| D001555 | Benzene Derivatives |
| D006841 | Hydrocarbons, Aromatic |
| D006844 | Hydrocarbons, Cyclic |
| D006838 | Hydrocarbons |
| D009930 | Organic Chemicals |
| D000813 | Anilides |
| D000577 | Amides |
| D000814 | Aniline Compounds |
| D000588 | Amines |