Topical 0.5% Ivermectin Cream for Treatment of Demodicidosis

a Randomised, Double Blind, Placebo Controlled, Half- Face Study to Evaluate the Effect of Topical Ivermectin Cream 0.5% on Demodicidosis

The purpose of this study is to determine whether 0.5% ivermectin cream is effective in the treatment of demodicidosis (including papulopustular rosacea)

Inclusion Criteria:

• subjects with clinical and laboratory diagnosis of demodicidosis with symmetrical facial eruption who are willing to comply with study requirements

Exclusion Criteria:

• known hypersensitivity to ivermectin.
• pregnancy
• immunodeficiency such as HIV or immunosuppressive therapy
• concomitant use of systemic antibiotics or steroids