CRRTNet Registry- A Prospective Observational Registry | NCT02034448

Studies
CRRTNet Registry- A Prospective Observational Registry

NCT02034448

Sponsor

AKI Critical Care Research Foundation

Status

Unknown status

Last Update Posted

Jan 14, 2015Estimated

Enrollment

2,000Estimated

Phase

Not provided

Conditions

Continuous Renal Replacement Therapy

Interventions

Continuous Renal Replacement Therapy

Countries

United States

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jan 2015

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Nov 2013

Primary Completion Date

Dec 2018Estimated

Completion Date

Dec 2018Estimated

First Submitted Date

Jan 10, 2014

First Submission Date that Met QC Criteria

Jan 10, 2014

First Posted Date

Jan 13, 2014Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jan 12, 2015

Last Update Posted Date

Jan 14, 2015Estimated

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Not provided

Is FDA Regulated Device

Not provided

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

An observational registry to monitor the outcome of CRRT in adults with acute kidney injury.

Detailed Description

Continuous Renal Replacement Therapy (CRRT) is a form of dialysis provided to critically ill patients with acute renal failure, now known as acute kidney injury (AKI). While we have extensive experience with this therapy in critically ill patients, there is no consensus on when to start CRRT or a clinical standard as to the best possible way to deliver the therapy. Previous studies have examined one aspect of CRRT in detail (for instance the dose of delivered therapy, or anticoagulation strategies) or have been small single center studies, or large multinational studies examining very basic practice patterns. This is a prospective observational cohort study. All patients who receive CRRT as part of their standard of local care will be eligible for the study.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

2,000Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Acute Kidney Injury		CRRT intervention with adult patients with Acute Kidney Injury	Procedure: Continuous Renal Replacement Therapy

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Continuous Renal Replacement Therapy	Procedure		Acute Kidney Injury

Measure	Description	Time Frame
Mortality		30 days

Measure	Description	Time Frame
Length of Stay		6 months

Eligibility Module

Eligibility Criteria

Inclusion Criteria: Patients initiating CRRT c. Age > 18 years of age and <89 year of age -

Exclusion Criteria: ˂ 18 years of age and > 89 year of age

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

89 Years

Standard Ages

AdultOlder Adult

Study Population

This is a prospective observational registry. A minimum sample size of 2000 patients with the detailed information being obtained would embody the largest and most detailed repository of adult CRRT patient information available.

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Mike Heung, MD	University of Michigan Hospital	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Mike Heung	Recruiting	Ann Arbor	Michigan	48109	United States

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
41904566	Derived	Kusirisin P, Lambert JW, Rewa OG, Neyra JA, Bagshaw SM; CRRTnet Investigator. Association between obesity and kidney outcomes in critically ill patients with acute kidney injury receiving continuous renal replacement therapy: a secondary analysis of the multicenter CRRTnet study. Crit Care. 2026 Mar 28;30(1):143. doi: 10.1186/s13054-026-05950-w.
28683729

ID	Term
D017582	Renal Replacement Therapy
D013812	Therapeutics
D005112	Extracorporeal Circulation
D013514	Surgical Procedures, Operative