Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages. It is a painful surgery and one of the methods to reduce post-operative pain is performing a regional anaesthesia technique. The current practice is to perform a femoral nerve block (FNB) which blocks the nerves supplying the knee joint and the thigh muscles (quadriceps). This provides effective analgesia. However, it also results in weakness of the quadriceps and may result in falls post-operatively.
Adductor canal block (ACB) is a new, alternative regional anaesthesia technique which is hypothesised to provide as effective analgesia, with less quadriceps weakness compared to FNB, hence potentially reducing the risk of falls post-operatively.
Investigators aim to study if the analgesia provided by ACB is as good as FNB while preserving quadriceps strength.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Femoral Nerve Block | Active Comparator | Femoral Nerve block performed with 0.5% Ropivacaine 30mls (150mg) |
|
| Adductor Canal block | Active Comparator | Adductor Canal block performed with 0.5% Ropivacaine 30mls (150mg) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ropivacaine | Drug | 30mls of 0.5% ropivacaine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Morphine consumption | first 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Pain scores | 1, 6, 12, 24, 48 | |
| Morphine consumption | 48 hours | |
| Side effects of opioids- sedation, nausea and vomiting |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| CTRU CGH | Contact | 67888833 |
| Name | Affiliation | Role |
|---|---|---|
| Yean Chin Lim, MBBS, MMed | Changi General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Changi General Hospital | Recruiting | Singapore | 529889 | Singapore |
Not provided
| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 48 hours |
| Quadriceps strength, ability to mobilise | 24, 48 hours |
| D012216 |
| Rheumatic Diseases |
| D000588 |
| Amines |