ED95 of Lidocaine 1.0% for Filling the Adductor Canal

An Estimate of the ED95 of Lidocaine 1.0% for Filling the Adductor Canal When Placing an Adductor Canal Block in Healthy Volunteers

The aim of this prospective dose finding study is to estimate the minimal effective volume (ED95) for lidocaine 1.0% for filling the adductor canal when placing an adductor canal block. We will apply the Continual Reassessment Method (CRM) for estimating the ED95 and use an MRI scan to evaluate the main objective and ensure spread to the distal part of the adductor canal.

Inclusion Criteria:

• 18-30 years
• Men
• American Society of Anesthesiologists' class 1
• Body Mass Index 18-25

Exclusion Criteria:

• Allergy to study medication
• Earlier trauma or surgery to the lower limb
• Diabetes Mellitus - Contraindications to MRI