Efficacy of Vitamin D and Calcium Supplementation on the Prevention of Recurrences in BPPV

Efficacy of Vitamin D and Calcium Supplementation on the Prevention of Recurrences in Benign Paroxysmal Positional Vertigo: A Prospective Multicenter Randomized Trial

The purpose of this study is to determine whether the supplementation of vitamin D and calcium prevents recurrences of benign paroxysmal positional vertigo in patients with vitamin D deficiency/insufficiency.

Inclusion Criteria:

• age 18 years or older
• brief episodes of vertigo induced by head motion
• a typical positioning nystagmus characteristic of BPPV
• no supplementation of vitamin D or calcium at the time of recruitment
• informed consent to participate in this study
• subject treated by repositioning maneuver

Exclusion Criteria:

• other identifiable disorders of the central nervous system
• supplementation of vitamin D or calcium at the time of recruitment
• pregnancy
• a history of an allergic reaction, or a medically significant adverse reaction to the investigational product
• contraindication to cholecalciferol and calcium carbonate