An echocardiogram using Definity contrast can provide the same information as the standard right heart catheterization.

Inclusion Criteria:

• Adult patients scheduled to undergo right heart catheterization at the George Washington University Hospital

Exclusion Criteria:

• Patients with known or suspected right-to-left bi-directional or transient right-to-left shunts or pulmonary arteriovenous malformations, previously documented moderate to severe tricuspid regurgitation or moderate to severe pulmonary regurgitation, evidence of right ventricular hypokinesis, or prior adverse reaction to Definity or hypersensitivity to perflutren