Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

Local injection of 5-fluorouracil into a chalazion (stye) is as effective as local injection of triamcinolone (steroid) and incision and curettage for treatment of chalazia.

This is a prospective randomized interventional study comparing four current standard-of-care treatments for chalazia: incision and curettage, local injection of triamcinolone, local injection of 5-FU, and local injection of combination triamcinolone/5-FU.

Inclusion Criteria:

• Single or multiple chalazia in a single eyelid

Exclusion Criteria:

• Chalazia present for less than one month and no previous injection or incision and curettage