The Effect of Concentrated Pomegranate Juice Consumption on Lipid Profile and Inflammatory Factors in Patients With Type 2 Diabetes

The aim of this study is to examine the effects of concentrated pomegranate juice on serum lipid profile and some inflammatory factors in patients with type 2 diabetes. Forty patients aged between 25-60 years old from both sexes are recruited. Patients consume 50gr/day concentrated pomegranate juice for 4 weeks. Anthropometric and blood pressure measurements, 3-days food-record questionnaire ,physical activity and fasting blood samples were collected at the beginning and at the end of the study. Fasting blood sugar, lipid profile, TNF- a, IL-6,hs -CRP and adiponectin levels are measured. LDL are calculated by formula. The participants are asked not to change their regular diet, medicine and activity during the study.

Inclusion Criteria:

• male or female 25 to 60 years old
• having type 2 diabetes for at least 6 month

Exclusion Criteria:

• pregnancy
• lactation
• cardiac disease
• hepatic disease
• respiratory disease
• chronic renal diseases
• acute or chronic inflammation
• retinopathy
• intake of antioxidant supplement
• insulin therapy
• sensitivity to concentrated pomegranate juice
• change oral drug for controlling blood glucose