Verification of the Safety of Early Discharge in Patients After Acute ST-segment Myocardial Infarction

Official Title Verification of the Safety of Early Discharge (Within 72 Hours) in Low Risk Patients After Acute ST-segment Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention. Open Randomized Study.

The aim of the study is to prove that early discharge (within 72 hours) in selected group of patients after myocardial infarction with elevations of ST-segment is feasible and safe

The aim of the study is to prove

• that early discharge (within 72 hours) in selected group of patients with low risk of follow-up complications after myocardial infarction with elevations of ST-segment, treated with primary percutaneous coronary intervention, is feasible and safe
• that early discharge is comparable with the group of patients, discharged in a standard way accordingly with present practice and physician´s decision (usually 4th-7th day), thus it is not associated with higher incidence of complications in 90th day after myocardial infarction

Inclusion Criteria:

• Signed informed consent
• Age ≥18 do ≤ 75 years
• Acute myocardial infarction with ST-segment elevation, treated with successful percutaneous coronary intervention within 12 hours from the onset of symptoms
• Left ventricle ejection fraction ≥ 45% by echocardiography
• Single- or two-vessel disease (stenosis of major epicardial artery ≥ 70%)
• Haemodynamic and rhythmic stability (Killip class I, no arrythmia requiring treatment occurring > 2 hours after PCI)
• Assumed good cooperation and social background

Exclusion Criteria:

• Symptoms of residual ischemia
• Significant comorbidities or abnormalities in paraclinical tests, requiring additional evaluation within continuing hospitalization
• Contraindication of dual antiplatelet therapy or need for anticoagulation therapy
• Hihg risk of bleeding complications
• Participation in other clinical study