Not provided
Not provided
Not provided
Not provided
Only 1 participant recruited to study. Qs addressed in other ongoing studies.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Objectives: This study will evaluate the efficacy of internet-based relapse prevention with therapist support, as compared to face-to-face therapy at an employee assistance program. The design is a two-armed randomized controlled design, and outcomes are measured in terms of changes in problematic alcohol use, as well as depression and quality of life.
Method: Participants with problematic alcohol use who, after an initial evaluation consisting of five face-to-face sessions with a licensed psychologist where alcohol and collateral problems are extensively assessed, are recommended treatment for problematic alcohol use. Consenting participants will be randomized into one of two groups: 1. Internet delivered relapse prevention with therapist support or 2. Face-to-face therapy. Outcomes on alcohol use, depression and quality of life as well as information on user satisfaction will be gathered post treatment. Follow up will be at 3, 6 and 12 months after completion.
Our hypothesis is that the internet-based program with therapist support and the face-to-face therapy will be equally effective in reducing alcohol use (non-inferiority).
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| eChange web-based relapse prevention | Experimental | A relapse intervention program consisting of 14 modules. Patients will have access to therapist support through an internal secure messaging system. |
|
| Face-to-face therapy | Active Comparator | Face-to-face psychotherapy, consisting of 20 sessions. The content will be vary for different therapists, but all have an evidence-based approach to therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| eChange | Behavioral | A web-based relapse intervention program consisting of 14 modules. The patient will have access to therapist support through a secure messaging system |
|
| Measure | Description | Time Frame |
|---|---|---|
| Alcohol Use Identification Test (AUDIT) | Change in total AUDIT score, as a summarized measure of alcohol use (including alcohol consumption and alcohol-related problems) | Post, 3, 6 and 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Time Line Follow Back (TLFB) | Change in total TLFB score, as a summarized measure of alcohol consumption | Post, 3, 6 and 12 months |
| Montgomery Asberg Depression Rating Scale - Self report (MADRS-S) |
| Measure | Description | Time Frame |
|---|---|---|
| Drug Use Identification Test (DUDIT) | Change in total DUDIT score, as a summarized measure of drug (including alcohol consumption and alcohol-related problems) | Post, 3, 6 and 12 months |
| Biological tests for alcohol markers |
Inclusion Criteria:
Problematic alcohol use and having been recommended psychotherapy by the assessing psychologist.
Exclusion Criteria:
Inadequate Swedish language skills No Internet access Reading and/or writing difficulties Major depression Current suicidal thoughts and/or plans Primary problematic drug use PTSD-related problems Psychosis Cognitive disability
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Anne H Berman, PhD | Karolinska Institutet | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Karolinska institutet, Department of Clinical Neuroscience | Stockholm | 171 76 | Sweden |
Not provided
| ID | Term |
|---|---|
| D000437 | Alcoholism |
| ID | Term |
|---|---|
| D019973 | Alcohol-Related Disorders |
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Face-to-face therapy | Behavioral | Face-to-face psychotherapy, consisting of 20 sessions. The content will be different for different therapists, but all have an evidence based approach to therapy |
|
Change in total MADRS-S score, as a summarized measure of depression
| Post, 3, 6 and 12 months |
| World Health Quality of Life Scale (WHOQOL-BREF) | Change in total WHOQOL-BREF score, as a summarized measure of quality of life | Post, 3, 6 and 12 months |
Biological marker outcomes post-treatment. B-PEth and CDT.
| Post |