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This is a Phase 2 randomized, multicenter, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy of HT-0712 in improving memory and cognitive performance in subjects with Age-Associated Memory Impairment (AAMI)
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HT-0712 (50mg) | Experimental | HT-0712 capsules administered once daily. |
|
| Placebo | Placebo Comparator | Placebo capsules administered once daily. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HT-0712 | Drug |
| ||
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive Drug Researchâ„¢ (CDR) Study Specific Test Battery | Weekly over the course of 6-weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Paired Associated Learning and Memory Test | Weekly over the course of 6-weeks | |
| Subject Global Impression Scale of Cognition (SGI-Cog) | Weekly over the course of 6-weeks |
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Main Inclusion Criteria:
Main Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Philip Perera, MD | Dart NeuroScience, LLC | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sun City | Arizona | United States | ||||
| Type | Date | Date Unknown |
|---|---|---|
| Release | Feb 7, 2018 | |
| Reset | Mar 6, 2018 | |
| Release | May 16, 2018 |
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|
| Long Beach |
| California |
| United States |
| Santa Monica | California | United States |
| Denver | Colorado | United States |
| Atlantis | Florida | United States |
| Brooksville | Florida | United States |
| Tampa | Florida | United States |
| Marlton | New Jersey | United States |
| Princeton | New Jersey | United States |
| New York | New York | United States |
| Dayton | Ohio | United States |
| Tulsa | Oklahoma | United States |
| Cordova | Tennessee | United States |
| Austin | Texas | United States |
| San Antonio | Texas | United States |
| Salt Lake City | Utah | United States |
| Reset | Jun 15, 2018 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Feb 7, 2018 | Mar 6, 2018 | |||
| May 16, 2018 | Jun 15, 2018 |
| ID | Term |
|---|---|
| C000599150 | HT-0712 |
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