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| ID | Type | Description | Link |
|---|---|---|---|
| 0033769 | Other Grant/Funding Number | National MS Society |
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Between 15-20% of MS patients decide not to initiate disease modifying therapies after being diagnosed with MS. For this study, we will develop a telephone-based talk therapy intervention and then conduct a randomized controlled trial. Patients will be assigned to either 5 weekly 20 minute telephone sessions of psychotherapy or a brief education control condition. We hypothesize that patients undergoing phone therapy will be more likely to indicate they are interested in initiating disease modifying medications than patients given brief education and treatment as usual.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Brief Education | Active Comparator | Patients receive a brief educational packet along with treatment as usual |
|
| MI-CBT Treatment | Experimental | Patients receive five 20 minute phone sessions of motivational interviewing/cognitive behavioral therapy weekly along with a brief educational packet. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Brief Education | Behavioral | Give patients a pamphlet discussing pros and cons of disease modifying therapies |
|
| Measure | Description | Time Frame |
|---|---|---|
| Adherence Treatment Survey | Whether the patient indicates if he/she decided to re-initiate disease modifying therapies on a "yes"/"no" question. | 10 weeks after enrollment |
| Measure | Description | Time Frame |
|---|---|---|
| Adherence Treatment Survey | Whether the patient reports that he/she plans to discuss disease modifying therapies with a care provider on a "yes"/"no" question. | 10 weeks after enrollment |
| Adherence Treatment Survey |
| Measure | Description | Time Frame |
|---|---|---|
| Motivation/Readiness Questionnaire | Whether there is increased self-reported motivation to take disease modifying therapies on a 1-10 likert-type scale. | 10 weeks after enrollment |
| Motivation/Readiness Questionnaire |
Inclusion Criteria:
Exclusion Criteria:
-
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Missouri-Kansas City | Kansas City | Missouri | 64110 | United States | ||
| Kessler Rehabilitation Institute |
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| ID | Term |
|---|---|
| D020529 | Multiple Sclerosis, Relapsing-Remitting |
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
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| Motivational Interviewing-Cognitive Behavioral Therapy | Behavioral | A telephone based talk therapy discussing pros and cons of medication use in MS. |
|
Whether the patient reports that he/she plans to discuss disease modifying therapies with a care provider on a "yes"/"no" question.
| 5 weeks after enrollment |
| Adherence Treatment Survey | Whether the patient indicates if he/she decided to re-initiate disease modifying therapies on a "yes"/"no" question. | 5 weeks after enrollment |
Whether there is increased self-reported motivation to take disease modifying therapies on a 1-10 likert-type scale.
| 5 weeks after enrollment |
| West Orange |
| New Jersey |
| 07052 |
| United States |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |