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Taurolidine alone or in combination with citrate have been proposed for locking the catheter to reduce the number of catheter infections. As there is not enough evidence to give recommendations in this regard, the study tested the hipothesis that taurolidine improves the outcome of long term paretneral nutrition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Placebo Comparator | Saline flush |
|
| 2% Taurolidine lock | Active Comparator | Catheter lock with 2% Taurolidine |
|
| 1.35% Taurolidine with citrate | Active Comparator | Catheter lock with 1.35% Taurolidine + citrate |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 2% Taurolidine Lock | Drug | Catheter lock with 2% Taurolidine |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of CVC infections | Number of central venous catheter infections | 12 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Stanislaw Klek, Assoc Prof | Stanley Dudrick's Memorial Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stanley Dudrick's Memorial Hospital | Skawina | 32-050 | Poland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19464090 | Background | Pittiruti M, Hamilton H, Biffi R, MacFie J, Pertkiewicz M; ESPEN. ESPEN Guidelines on Parenteral Nutrition: central venous catheters (access, care, diagnosis and therapy of complications). Clin Nutr. 2009 Aug;28(4):365-77. doi: 10.1016/j.clnu.2009.03.015. Epub 2009 May 21. |
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| ID | Term |
|---|---|
| C012566 | taurolidine |
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| 1.35% Taurolidine | Drug | Catheter lock with 1.35% Taurolidine + citrate |
|