Effect of Colloid Versus Crystalloid on Coagulation in Elective Urological Surgery

Effect of Colloid Versus Crystalloid on Coagulation in Elective Urological Surgery. A Randomised Clinical Study

The purpose of this study is to investigate the effect of thin fluid with starch versus thin fluid without starch on coagulation in elective surgery when the patient is normovolæmic during operation.

The primary goal is to register coagulation on basis of blood samples inclusive thromboelastography results.

The secondary goal is to register blood loss and use of blood products during operation.

The trial concerns 40 patients.

Inclusion Criteria:

• Patient older than 18 years.
• Indication for elective surgery with removal of the urine bladder.
• Patient without anticoagulative, acethylsalisylsyre or NSAID medicine during the last 5 days,if using.

Exclusion Criteria:

• Cerebral haemorrhage
• Renal insufficiency demanding dialysis
• Manifest cardiac and hepatic insufficiency
• Disturbance in coagulation
• Hypernatriæmi
• Hyperchloræmi
• Pregnant or nursing
• Allergic to hydroxyethylstarch
• Participating in another trial-if interferring the present trial
• Incapable of managing his own affairs.