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Define the patients who lost HBsAg, studying the loss predictive factors and if there was suspension of treatment, study the evolution after that
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with chronic hepatitis B treated with nRTI | Patients with chronic hepatitis B with HBsAg loss treated with nucleoside/nucleotide analogues (Lamivudine, Adefovir, Tenofovir, Telbivudine, Entecavir, Emtricitabine) |
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| Measure | Description | Time Frame |
|---|---|---|
| Epidemiological characteristics from hepatitis B patients who lost HBsAg related to treatment with nucleoside/nucleotide analogues | Study the number of diferents virological, serological, clinical, histological, biochemical characteristics from hepatitis B patients who lost HBsAg related to treatment with nucleoside/nucleotide analogues. | 15 months |
| Measure | Description | Time Frame |
|---|---|---|
| Epidemiological characteristics in case of suspension of treatment. | Count the diferents characteristics virological, histological, serological, and the clinical course of this patients whom must to be suspended the treatment | 15 months |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with chronic hepatitis B with HBsAg loss treated with nucleoside/nucleotide analogues
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| Name | Affiliation | Role |
|---|---|---|
| Emilio Suárez García | Hospital Universitario Virgen de Valme | Principal Investigator |
| Miguel Ángel Simón Marco | Hospital Clínico Universitario Lozano Blesa | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Germans Trias i Pujol | Badalona | Barcelona | Spain | |||
| Hospital Universitario Bellvitge |
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| L'Hospitalet de Llobregat |
| Barcelona |
| Spain |
| Complejo Hospitalario Universitario Santiago | Santiago de Compostela | La Coruña | Spain |
| Hospital Severo Ochoa | Leganés | Madrid | Spain |
| Hospital Torrecárdenas | Almería | Spain |
| Hospital Clínic | Barcelona | Spain |
| Hospital del Mar | Barcelona | Spain |
| Hospital Universitario Vall d'Hebron | Barcelona | Spain |
| Hospital Universitario Reina Sofía | Córdoba | Spain |
| Hospital Puerta de Hierro | Madrid | Spain |
| Hospital Universitario Central de Asturias | Oviedo | Spain |
| Hospital de Navarra | Pamplona | Spain |
| Hospital Donosti | San Sebastián | Spain |
| Hospital Marqués de Valdecilla | Santander | Spain |
| Hospital Universitario Virgen de la Macarena | Seville | Spain |
| Hospital Universitario Virgen de Valme | Seville | Spain |
| Hospital Universitario Virgen del Rocío | Seville | Spain |
| Hospital Virgen de la Salud | Toledo | Spain |
| Hospital General Universitario de Valencia | Valencia | Spain |
| Hospital La Fe | Valencia | Spain |
| Hospital Clínico Universitario Lozano Blesa | Zaragoza | Spain |
| Hospital Miguel Servet | Zaragoza | Spain |
| ID | Term |
|---|---|
| D006509 | Hepatitis B |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D018347 | Hepadnaviridae Infections |
| D004266 | DNA Virus Infections |
| D014777 | Virus Diseases |
| D006525 | Hepatitis, Viral, Human |
| D006505 | Hepatitis |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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