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| Name | Class |
|---|---|
| Radiation Therapy Oncology Group | NETWORK |
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This study will evaluate the proportion of prostate cancer patients receiving external beam radiation therapy (EBRT) and androgen deprivation therapy (ADT) with controlled blood sugars (fasting glucose and hemoglobin A1c), blood pressure, and cholesterol profile (total cholesterol, LDL, HDL, triglycerides) at baseline, 3 months, and 12 months after completing radiation treatment. In addition, receipt of guideline-recommended cardiovascular, primary and preventive care as well as patient-reported quality of life and satisfaction with care among these patients will be evaluated at baseline and 12 months.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non-metastatic prostate cancer patients | Histologically-confirmed, non-metastatic prostate cancer patients who received external beam radiation treatment with androgen deprivation therapy (total ADT duration > 3 months) for definitive treatment. |
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| Measure | Description | Time Frame |
|---|---|---|
| Proportion of prostate cancer patients with controlled blood sugars, blood pressure, and cholesterol profile. | Blood sugars include fasting glucose and hemoglobin A1c; blood pressure includes systolic and diastolic; and cholesterol profile includes total cholesterol, LDL, HDL, and triglycerides. Baseline is prior to receiving androgen deprivation therapy and prior to radiation. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of prostate cancer patients with controlled blood sugars, blood pressure, and cholesterol profile. | Blood sugars include fasting glucose and hemoglobin A1c; blood pressure includes systolic and diastolic; and cholesterol profile includes total cholesterol, LDL, HDL, and triglycerides. | 3 months post radiation treatment completion |
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Inclusion Criteria:
Exclusion Criteria:
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Histologically-confirmed, non-metastatic prostate cancer patients who visit radiation oncology clinics at participating institutions: The University of North Carolina at Chapel Hill Cancer Hospital, Rex Cancer Center at the Raleigh and Wakefield locations, Marion J. Shepard Cancer Center, Coastal Carolina Radiation Oncology, The University of Virginia, High Point Regional UNC Health Care, and MedStar Georgetown University. Patients with planned radiation treatment and androgen deprivation therapy with curative intent (in definitive or post-prostatectomy settings) are eligible.
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| Name | Affiliation | Role |
|---|---|---|
| Ronald C Chen, MD, MPH | University of North Carolina at Chapel Hill - Department of Radiation Oncology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | United States | ||
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| Label | URL |
|---|---|
| UNC Lineberger Comprehensive Cancer Center | View source |
| National Cancer Institute | View source |
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| Proportion of prostate cancer patients with controlled blood sugars, blood pressure, and cholesterol profile. |
Blood sugars include fasting glucose and hemoglobin A1c; blood pressure includes systolic and diastolic; and cholesterol profile includes total cholesterol, LDL, HDL, and triglycerides. |
| 12 months post radiation treatment completion |
| Proportion of prostate cancer patients with guideline-recommended cardiovascular preventive care (glucose testing, cholesterol testing, and blood pressure measurement). | This will be done by patient self-report and by medical record review (radiation oncologist will obtain medical records from patient's primary care physician). | Baseline |
| Proportion of prostate cancer patients with guideline-recommended cardiovascular preventive care (glucose testing, cholesterol testing, and blood pressure measurement). | This will be done by patient self-report and by medical record review (radiation oncologist will obtain medical records from patient's primary care physician). | 12 months post radiation treatment completion |
| Proportion of prostate cancer patients who receive other (non-cardiovascular) guideline-recommended primary and preventive care (flu vaccination, colorectal cancer screening, and healthy lifestyle counseling). | This will be done by patient self-report and by medical record review (radiation oncologist will obtain medical records from patient's primary care physician). | Baseline |
| Proportion of prostate cancer patients who receive other (non-cardiovascular) guideline-recommended primary and preventive care (flu vaccination, colorectal cancer screening, and healthy lifestyle counseling). | This will be done by patient self-report and by medical record review (radiation oncologist will obtain medical records from patient's primary care physician). | 12 months post radiation treatment completion |
| Patient-reported quality of life. | Baseline |
| Patient-reported quality of life. | 12 months post radiation treatment completion |
| Patient-reported coordination of care. | Baseline |
| Patient-reported coordination of care. | 12 months post radiation treatment completion |
| Patient-reported satisfaction with care. | Baseline |
| Patient-reported satisfaction with care. | 12 months post radiation treatment completion |
| University of North Carolina at Chapel Hill Cancer Hospital |
| Chapel Hill |
| North Carolina |
| 27599 |
| United States |
| High Point Regional UNC Health Care | High Point | North Carolina | 27262 | United States |
| Rex Healthcare, Inc | Raleigh | North Carolina | 27607 | United States |
| Rex Healthcare of Wakefield | Raleigh | North Carolina | 27614 | United States |
| Marion L. Shepard Cancer Center | Washington | North Carolina | 27889 | United States |
| Coastal Carolina Radiation Oncology | Wilmington | North Carolina | 28401 | United States |
| University of Virginia | Charlottesville | Virginia | 22908 | United States |
| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D005832 | Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |
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