Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Our hypothesis is that there will be a decrease in internal jugular venous flow in the park bench position when compared to the supine position. There will also be a change in blood flow in the between right and left internal jugular veins in park bench position, particularly there will be a greater reduction of flow on the dependent side. However, the internal jugular venous flow will be the same in both the prone and supine position.
The different positions used in neurosurgery (park bench, prone) for better accessibility to the operating field can impact on the cerebral venous drainage due to the effects of internal jugular venous outflow of blood and may increase intracranial pressure. The kinking of the internal jugular vein due to excessive neck flexion and rotation in park bench or flexion in the prone position may lead to kinking or twisting of the vein. This has been hypothesized as the major cause of disturbed venous drainage during surgery and in postoperative patients may lead to neck swelling, brachial plexus injury, macroglossia (swollen tongue), delayed airway obstruction and increases in intracranial pressure.
Optimal brain perfusion is best in the neutral position of the head, but surgery cannot always be performed with this. Thus, we look to measure the internal jugular venous flow at different positions as there have been little studies looking at this important contributing factor.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| volunteers in different positions | The following will be compared in the same volunteer:
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Different positions | Other | Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench |
|
| Measure | Description | Time Frame |
|---|---|---|
| Internal Jugular Venous (IJV) Cross Sectional Area | Comparisons of both jugular vein (IJV) of twenty-seven volunteers in supine and prone positions. | 1 day |
| Right and Left IJV Cross Sectional Area | Twenty-seven volunteers were included in this study. Comparisons of cross sectional area measurements in both IJVs between supine and right park bench | 1 day |
| Internal Jugular Venous (IJV) Doppler Velocity | 27 volunteers enrolled to measure the Internal Jugular Venous (IJV) in supine and prone positions | 1 day |
| Bilateral Internal Jugular Vein (IJV) Flow | Comparisons of bilateral internal jugular vein (IJV) flow between supine and prone position. Data presented as mean (SD) . | 1 day |
| Bilateral Internal Jugular Vein (IJV) Doppler Velocity | Comparisons of bilateral internal jugular vein (IJV) Doppler velocity between supine and right park bench position. | 1 day |
| R IJV and L IJV Flow | Bilateral internal jugular vein (IJV) flow between supine and right park bench position. | 1 day |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Healthy Volunteers
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Lashmi Venkatraghavan | University Health Network, Toronto Western Hospital | Principal Investigator |
| Vincent Chan | University Health Network, Toronto Western Hospital | Principal Investigator |
| Pirjo Manninen | University Health Network, Toronto Western Hospital | Principal Investigator |
| Audrey MY Tan | University Health Network, Toronto Western Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Health Network, Toronto Western Hospital | Toronto | Ontario | M5T 2S8 | Canada |
Twenty-seven volunteers were included in this study.
Not provided
Not provided
| ID | Title | Description |
|---|---|---|
| FG000 | Volunteers in Different Positions | The following will be compared in the same volunteer:
|
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
Twenty-seven volunteers were included in this study. The mean (SD) age, height and weight of these participants were analyzed.
Not provided
| ID | Title | Description |
|---|---|---|
| BG000 | Volunteers in Different Positions | The following will be compared in the same volunteer:
Different positions: Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Customized | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Internal Jugular Venous (IJV) Cross Sectional Area | Comparisons of both jugular vein (IJV) of twenty-seven volunteers in supine and prone positions. | Twenty-seven volunteers were included in this study. Comparisons of right and left internal jugular vein (IJV) cross sectional area, Doppler velocity and flow between supine and prone position. | Posted | Mean | Standard Deviation | cm2 | 1 day |
|
1 day
Not provided
Not provided
| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Volunteers in Different Positions | The following will be compared in the same volunteer:
Different positions: Jugular venous blood flow in healthy volunteers in 3 different positions- supine, prone and park bench |
Not provided
Not provided
Not provided
| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Emad Al Azazi | Toronto Western Hospital/UHN | 416-603-8500 | 6237 | emad.alazazi@uhnresearch.ca |
Not provided
Not provided
Not provided
Not provided
| years |
|
| Sex/Gender, Customized | Number | participants |
|
| Height | Mean | Standard Deviation | units on a scale |
|
| Weight | Mean | Standard Deviation | units on a scale |
|
|
|
| Primary | Right and Left IJV Cross Sectional Area | Twenty-seven volunteers were included in this study. Comparisons of cross sectional area measurements in both IJVs between supine and right park bench | Comparisons of bilateral internal jugular vein (IJV) cross sectional area, Doppler velocity and flow between supine and right park bench position. | Posted | Mean | Standard Deviation | cm2 | 1 day |
|
|
|
| Primary | Internal Jugular Venous (IJV) Doppler Velocity | 27 volunteers enrolled to measure the Internal Jugular Venous (IJV) in supine and prone positions | Comparisons of bilateral internal jugular vein (IJV) Doppler velocity between supine and prone position. Data presented as mean (SD) . | Posted | Mean | Standard Deviation | cm.sec-1 | 1 day |
|
|
|
| Primary | Bilateral Internal Jugular Vein (IJV) Flow | Comparisons of bilateral internal jugular vein (IJV) flow between supine and prone position. Data presented as mean (SD) . | Comparisons of bilateral internal jugular vein (IJV) flow between supine and prone position. Data presented as mean (SD) . | Posted | Mean | Standard Deviation | ml.min-1 | 1 day |
|
|
|
| Primary | Bilateral Internal Jugular Vein (IJV) Doppler Velocity | Comparisons of bilateral internal jugular vein (IJV) Doppler velocity between supine and right park bench position. | Comparisons of bilateral internal jugular vein (IJV) cross sectional area, Doppler velocity and flow between supine and right park bench position. Data presented as mean (SD). | Posted | Mean | Standard Deviation | cm.sec-1 | 1 day |
|
|
|
| Primary | R IJV and L IJV Flow | Bilateral internal jugular vein (IJV) flow between supine and right park bench position. | Comparisons of bilateral internal jugular vein (IJV) flow between supine and right park bench position. Data presented as mean (SD). | Posted | Mean | Standard Deviation | ml.min-1 | 1 day |
|
|
|
| 0 |
| 27 |
| 0 |
| 27 |
| 0 |
| 27 |
Not provided
Not provided
Not provided