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RE-ACT is a national, multi-centre, observational, prospective, longitudinal cohort study which will include patients hospitalized for ACS within 24 hours of symptom onset and who have a final diagnosis of ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI). This study aims to describe the short-term (at the end of the first month after index event) antithrombotic management patterns in a "real-life" setting for patients hospitalized with an acute coronary syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with STEMI and NSTEMI | Patients aged 18 years or older, hospitalized and diagnosed with STEMI (ST-segment elevation myocardial infarction) or NSTEMI (non-ST-segment elevation myocardial infarction) within 24 hours of symptom onset. |
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| Measure | Description | Time Frame |
|---|---|---|
| Short-term antithrombotic management patterns (AMPs) in a real-life setting for patients hospitalized with an ACS | Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage). Antithrombotic management patterns will be grouped taking into account only the different treatment options shown by the descriptive analysis. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Variations in the acute clinical management strategies and AMPs. | Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage). | Baseline |
| Impact of the different AMPs on quality of life at discharge from hospital (using EuroQoL-5D). |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged 18 years or older, hospitalized and diagnosed with STEMI (ST-segment elevation myocardial infarction) or NSTEMI (non-ST-segment elevation myocardial infarction) within 24 hours of symptom onset.
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| Name | Affiliation | Role |
|---|---|---|
| Elina Trendafilova, Ass. Prof. M.D | National Cardiology Hospital, Sofia | Principal Investigator |
| Vasil Velchev, Ass. Prof. M.D. | University Hospital St. Anna | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Site | Blagoevgrad | Bulgaria | ||||
| Research Site |
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| ID | Term |
|---|---|
| D054058 | Acute Coronary Syndrome |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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Descriptive statistics will be calculated for this outcome measure using frequency tables (n, mean, median, standard deviation, minimum and maximum) |
| Baseline |
| Impact of the different AMPs on quality of life at the end of the first month after discharge from the hospital (using EuroQoL-5D). | Descriptive statistics will be calculated for this outcome measure using frequency tables (n, mean, median, standard deviation, minimum and maximum) | At the end of the first month after index event |
| Determinants of AMP choices (i.e. patient's characteristics, hospital characteristics, coronary intervention strategies and type of coronary stents used) | Descriptive statistics will be calculated for this outcome measure using frequency tables (n, frequency and percentage). | Baseline |
| Burgas |
| Bulgaria |
| Research Site | Lovech | Bulgaria |
| Research Site | Plovdiv | Bulgaria |
| Research Site | Rousse | Bulgaria |
| Research Site | Sofia | Bulgaria |
| Research Site | Varna | Bulgaria |
| Research Site | Vratsa | Bulgaria |