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The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| nitroprusside | Experimental | After induction of anesthesia, controlled hypotension was induced with continuous infusion of nitroprusside. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK). |
|
| remifentanil | Experimental | After induction of anesthesia, controlled hypotension was induced with continuous infusion of remifentanil. Cardiac index, stroke volume index, and total peripheral resistance index were continuously measured using noninvasive cardiac output monitor (Cheetah NICOM, Cheetah Medical Inc, UK). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| remifentanil | Drug |
| ||
| nitroprusside |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiac index | Cardiac index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of cardiac index during controlled hypotension was compared with baseline value. | Cardiac index was continuously measured during controlled hypotension, an average of 90 min |
| Measure | Description | Time Frame |
|---|---|---|
| Total peripheral resistance index | Total peripheral resistance index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of total peripheral resistance index during controlled hypotension was compared with baseline value. | Total peripheral resistance index was continuously measured during controlled hypotension, an average of 90 min |
| Measure | Description | Time Frame |
|---|---|---|
| Stroke volume index | Stroke volume index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of stroke volume index during controlled hypotension was compared with baseline value. | Stroke volume index was continuously measured during controlled hypotension, an average of 90 min |
Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jeju National University Hospital | Jeju City | Jeju Special Self-Governing Province | 690-767 | South Korea |
| Type | Date | Date Unknown |
|---|---|---|
| Release | Apr 2, 2015 | |
| Reset | Apr 14, 2015 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Apr 2, 2015 | Apr 14, 2015 |
| ID | Term |
|---|---|
| D007022 | Hypotension |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D000077208 | Remifentanil |
| D009599 | Nitroprusside |
| ID | Term |
|---|---|
| D011422 | Propionates |
| D000144 | Acids, Acyclic |
| D002264 | Carboxylic Acids |
| D009930 | Organic Chemicals |
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|
| D010880 |
| Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D005292 | Ferricyanides |
| D003486 | Cyanides |
| D000838 | Anions |
| D007477 | Ions |
| D004573 | Electrolytes |
| D007287 | Inorganic Chemicals |
| D005290 | Ferric Compounds |
| D058085 | Iron Compounds |
| D006856 | Hydrogen Cyanide |
| D017672 | Nitrogen Compounds |