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| Name | Class |
|---|---|
| Stockholm University | OTHER |
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The main purpose of this study is to investigate the effects of partial sleep deprivation (PSD) on resting state brain connectivity, emotional contagion, empathy, and emotional regulation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sleep deprivation | Experimental | Partial sleep deprivation allowing 3 h sleep at night |
|
| Full sleep | Experimental | Sleep with no restriction |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Partial sleep deprivation allowing 3 h sleep at night | Behavioral | Participants sleep at home while monitored with ambulatory polysomnography. For the full sleep condition, they are instructed to go to bed and to get up at the usual times that they would normally do that. For the sleep deprivation condition, they are instructed to go to bed 3 hours before the time when they would usually get up, and then to get up at that time. |
| Measure | Description | Time Frame |
|---|---|---|
| Blood oxygen level-dependent response in amygdala to angry faces (t/z-score from statistical parametric mapping) | This registration is made in order to pre-specify hypotheses in a basic science project. For a full list of outcomes and hypotheses, see study description (above). | Change between 1st and 2nd MRI scanning session (approx. 1 month later) |
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Inclusion Criteria:
20-30 years of age, inclusive OR 65-75 years of age, inclusive
Able to understand spoken and written Swedish (in order to understand instructions)
Normal or corrected-to-normal vision not using glasses
Not colour blind
Right-handed
Free from ferromagnetic objects in body
No history of any neurologic or psychiatric illness including drug abuse
No history of diabetes nor hypertension
No use of psychotropic drugs
Not studying or working in medicine, psychology, nor behavioural science
Not suffering from severe seasonal allergy
No use of cortisone, anti-histamines, nor any other immune-modulating drugs
Habitual intake of no more than 4 cups of coffee per day or the equivalent in terms of caffeine
No daily use of nicotine
Exclusion Criteria:
-
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| Name | Affiliation | Role |
|---|---|---|
| Torbjörn Åkerstedt, PhD | Stockholm University | Study Chair |
| Mats Lekander, PhD | Stockholm University, Karolinska Institutet | Principal Investigator |
| HÃ¥kan Fischer, PhD | Stockholm University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Karolinska Institutet, Karolinska Universitetssjukhuset i Solna | Stockholm | None/Not Applicable | SE-17177 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39241898 | Derived | Tian Y, Peng XR, Tang Z, Long Z, Xie C, Lei X. Enhanced diversity on connector hubs following sleep deprivation: Evidence from diffusion and functional magnetic resonance imaging. Neuroimage. 2024 Oct 1;299:120837. doi: 10.1016/j.neuroimage.2024.120837. Epub 2024 Sep 4. | |
| 33087746 | Derived | Tamm S, Schwarz J, Thune H, Kecklund G, Petrovic P, Akerstedt T, Fischer H, Lekander M, Nilsonne G. A combined fMRI and EMG study of emotional contagion following partial sleep deprivation in young and older humans. Sci Rep. 2020 Oct 21;10(1):17944. doi: 10.1038/s41598-020-74489-9. |
| Label | URL |
|---|---|
| List of hypotheses | View source |
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De-identified individual participant data will be shared through the openfmri.org data repository.
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Oct 13, 2017 | |
| Reset | Jul 23, 2018 | |
| Release | Apr 3, 2019 | |
| Reset | Jun 27, 2019 | |
| Release | Oct 18, 2023 | |
| Reset | Apr 12, 2024 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Oct 13, 2017 | Jul 23, 2018 | |||
| Apr 3, 2019 |
| ID | Term |
|---|---|
| D012892 | Sleep Deprivation |
| D000080103 | Emotional Regulation |
| ID | Term |
|---|---|
| D020920 | Dyssomnias |
| D012893 | Sleep Wake Disorders |
| D009422 | Nervous System Diseases |
| D009461 | Neurologic Manifestations |
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|
| Full sleep | Behavioral | Participants sleep at home while monitored with ambulatory polysomnography. For the full sleep condition, they are instructed to go to bed and to get up at the usual times that they would normally do that. For the sleep deprivation condition, they are instructed to go to bed 3 hours before the time when they would usually get up, and then to get up at that time. |
|
| Jun 27, 2019 |
| Oct 18, 2023 | Apr 12, 2024 |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001523 | Mental Disorders |
| D000068356 | Self-Control |
| D012919 | Social Behavior |
| D001519 | Behavior |