Electrophysiologic Parameters and Biomarkers Predicting Treatment Response in Patients With Major Depressive Disorder

Phase 4 Study of Escitalopram Treatment and Biomarkers in Major Depressive Disorder

To explore electrophysiologic parameters and biomarkers predicting treatment response of patients with major depressive disorder To explore electrophysiologic parameters and biomarkers predicting suicide risk of patients with major depressive disorder

Case-control study Repeated measures design

Inclusion Criteria:

• DSM-IV-TR major depressive disorder
• aged between 20 and 80
• durg-naive or drug-free

Exclusion Criteria:

• DSM-IV-TR substance-related disorders (except nicotine)
• significant medical or neurological conditions
• mental retardation or organic brain damage