Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS | NCT01996670 | Trialant
CompletedObservationalUpdated Nov 27, 2013
Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS
ClinicalTrials.gov ID
NCT01996670
Lead Sponsor
Xiangya Hospital of Central South UniversityOTHER
Overall Status
Completed
Study Type
Observational
Enrollment
683Actual
Last Update Posted
Nov 27, 2013Estimated
Start Date
Jan 2007
Primary Completion Date
Dec 2012Actual
Brief Summary
We hypothesis a period of early NCPAP before surfactant treatment is effective for treating RDS and preventing BPD in very premature infants.
Nasal Continuous Positive Airway Pressure,
Preterm Infants,
Surfactant Treatment,
Respiratory Distress Syndrome,
Bronchopulmonary Dysplasia
No interventions
There are no interventions for this study.
Ages Eligible for Study
Child (0-17)
Sexes Eligible for Study
All
Accepts Healthy Volunteers
No
Eligibility Criteria
Inclusion Criteria:
All enrolled infants were able to breathe at 5 min of age, had evidence of respiratory distress, unable to receive surfactant therapy, and were administrated with early NCPAP as the initial treatment
Exclusion Criteria:
Exclusion criteria were endotracheal intubation for resuscitation or insufficient respiratory drive, died in the first 24 hours after birth, known genetic disorders, potentially life-threatening conditions unrelated to prematurity, and premature rupture of membranes (PROM) for >3 weeks.