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| Name | Class |
|---|---|
| TRYG Foundation | OTHER |
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The purpose of the study is to test an intervention aiming to reduce sitting time during work hours among office workers.
Expectations according to outcome measures: Sitting time reduced by 1 hour pr. day (primary). Number of prolonged periods reduced by 1 pr. day (primary). Number of breaks increased by 3 pr. day (primary). 20 % of participants report a reduction of musculoskeletal pain (secondary). A reduction in waist circumference of 1 cm (secondary). A reduction of 0.5 % in bodyfat (secondary).
Background and aim: Sedentary behaviour has substantial impact on wellbeing and health, e.g. on the risk of cardiovascular disease and premature death. These associations seem to apply as well to people who carry out the recommended 30 minutes of physical activity per day. However, studies indicate that the harmful effects can be reduced through breaking prolonged periods of sitting by intervals of standing or walking.
In total 46 % of Danes are working in occupations which are primarily sedentary and the workplace is thus a relevant setting to intervene against sedentary behaviour.
The aim of the study is to test an intervention towards sitting time among office workers. The intervention will target both total sitting time, breaks from sitting and prolonged periods of sitting.
Design: Cluster-randomized control study led at four different workplaces in Denmark and Greenland. Each workplace should consist of four independent sections (clusters) of about 25 people. Those four sections are randomized to intervention or control. A cluster design is used because the intervention will target the workplace setting as a whole, thus individuals within the same office has to be randomized to the same arm of the intervention.
Participants: 400 adults with sedentary office-based work. Subjects should understand Danish and be without disabilities or diseases affecting their ability to stand or walk.
Intervention: Participating clusters are randomized to
Methods: Data on sedentary behaviour is collected objectively using ActiGraph. Waist circumference and body fat percentage is measured. Questionnaire data will be collected on background variables, physical activity level, workplace conditions and well-being.
Data will be collected at baseline, and after 1 and 3 months.
Analysis will be carried out following the intention-to-treat principle comparing the intervention and control group. We will use several outcomes and include baseline values as a covariate (ANCOVA). In addition we will use multilevel models to account for the hierarchical structure of data (workplace, cluster and participant).
Process evaluation will be conducted by the use of qualitative interviews and questionnaire data and concern both adoptions, implementation and sustainability of the intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental | Intervention group |
|
| Intervention control | Placebo Comparator | Control group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intervention group | Behavioral | The intervention consists of four components, which as described below:
|
| Measure | Description | Time Frame |
|---|---|---|
| Reduced total time spend sitting at work | Method of measurement: ActiGraph, average daily sitting time during work hours. | 1 month |
| Reduced number of prolonged siting periods (>30 min) | Method of measurement: ActiGraph, number of periods sitting >30 min. | 1 month |
| Increased number of breaks from sitting time | Method of measurement: ActiGraph, number of postural shifts from sitting to standing/walking | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Reduced musculoskeletal problems | Method of measurement: Questionnaire | 1 month |
| Waist circumference | Method of measurement: Waist circumference measurement |
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Inclusion Criteria:
Workplaces should be:
Individuals should be:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Janne S Tolstrup, MD, PhD | National Institute of Public Helath - University of Southern Denmark | Study Director |
| Morten Grønbæk, MD PhD | Centre for Intervention Research in HEalth Promotion and Disease Prevention | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Institute of Public Health - University of Southern Denmark | Copenhagen | 1353 | Denmark |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27094749 | Result | Danquah IH, Kloster S, Holtermann A, Aadahl M, Bauman A, Ersboll AK, Tolstrup JS. Take a Stand!-a multi-component intervention aimed at reducing sitting time among office workers-a cluster randomized trial. Int J Epidemiol. 2017 Feb 1;46(1):128-140. doi: 10.1093/ije/dyw009. | |
| 32770969 | Derived | Danquah IH, Kloster S, Tolstrup JS. "Oh-oh, the others are standing up... I better do the same". Mixed-method evaluation of the implementation process of 'Take a Stand!' - a cluster randomized controlled trial of a multicomponent intervention to reduce sitting time among office workers. BMC Public Health. 2020 Aug 8;20(1):1209. doi: 10.1186/s12889-020-09226-y. |
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| ID | Term |
|---|---|
| D057185 | Sedentary Behavior |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
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|
| Control group | Behavioral | The control group receives the intervention after the last follow-up, the exact time will be settled together with each workplace in the control group. |
|
| 3 month |
| Body fat percentage | Method of measurement: Body fat % is measured using a segmental body composition analyser | 3 months |
| Reduced total time spend sitting at work | Method of measurement: ActiGraph, average daily sitting time during work hours | 3 months |
| Reduced number of prolonged siting periods (>30 min) | Method of measurement: ActiGraph, number of periods sitting >30 min | 3 months |
| Increased number of breaks from sitting time | Method of measurement: ActiGraph, number of postural shifts from sitting to standing/walking | 3 months |
| 31626067 | Derived | Danquah IH, Tolstrup JS. Does It Work for Everyone? The Effect of the Take a Stand! Sitting-Intervention in Subgroups Defined by Socio-Demographic, Health-Related, Work-Related, and Psychosocial Factors. J Occup Environ Med. 2020 Jan;62(1):30-36. doi: 10.1097/JOM.0000000000001737. |
| 29897943 | Derived | Danquah IH, Pedersen ESL, Petersen CB, Aadahl M, Holtermann A, Tolstrup JS. Estimated impact of replacing sitting with standing at work on indicators of body composition: Cross-sectional and longitudinal findings using isotemporal substitution analysis on data from the Take a Stand! study. PLoS One. 2018 Jun 13;13(6):e0198000. doi: 10.1371/journal.pone.0198000. eCollection 2018. |
| 28368549 | Derived | Danquah IH, Kloster S, Holtermann A, Aadahl M, Tolstrup JS. Effects on musculoskeletal pain from "Take a Stand!" - a cluster-randomized controlled trial reducing sitting time among office workers. Scand J Work Environ Health. 2017 Jul 1;43(4):350-357. doi: 10.5271/sjweh.3639. Epub 2017 Apr 3. |
| 27914468 | Derived | Pedersen ES, Danquah IH, Petersen CB, Tolstrup JS. Intra-individual variability in day-to-day and month-to-month measurements of physical activity and sedentary behaviour at work and in leisure-time among Danish adults. BMC Public Health. 2016 Dec 3;16(1):1222. doi: 10.1186/s12889-016-3890-3. |
| D008722 | Methods |