Prevalence of MTHFR Polymorphisms in Venous Disease

Prevalence of MTHFR Polymorphisms in Venous Disease With or Without Concomitant Thrombosis

The etiologies of varicose veins and the progression to more serious forms of chronic venous disease and identification of appropriate diagnostic tests to better aid patient management by identifying individuals who may benefit from more aggressive treatment and/ or prophylactic measures.

Inclusion Criteria:

• Age 18 or over
• No venous disease (N=30); or C2-C3 venous disease (N=30); or C4-C6 venous disease (N=30)

Exclusion Criteria:

• Pregnancy

• Cancer

• Chronic obstructive pulmonary disease (COPD)

• Any systemic inflammatory disease

• Any of the following within the previous 30 days:

  • Trauma
  • Any surgery
  • Periods of prolonged inactivity