The purpose of this study is to retrieve and cryopreserve ovarian tissue from females undergoing a treatment that may lead to irreversible loss of ovarian function.

The aim of this preliminary study is to retrieve and properly cryopreserve ovarian tissue for autotransplantation in any premenopausal female whose ovarian function is threatened in a physiological, pathological or iatrogenic manner in an effort to observe the return of ovarian endocrine function and development of egg(s) appropriate for use in in vitro fertilization.

Inclusion Criteria:

• Patient must be female.
• Patient must have a disease process where the disease or its treatment adversely affects ovarian function.
• Patient must be recommended for this study by their oncologist or specialist.
• Patient (or legally authorized representative) must sign an informed consent.

Exclusion Criteria:

• Patients cannot be male.
• Patients must not be HIV positive.
• Patient cannot have a poor diagnosis such that she is not expected to survive to adulthood.
• Patient cannot have any medical condition that would contraindicate surgery.
• Patient cannot have any medical condition that would contraindicate general anesthesia.
• Patient cannot have any medical condition that would contraindicate pregnancy.