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We hypothesize that premature infants who receive their mothers' expressed breast milk supplemented with liquid protein early in their hospitalization will have a growth velocity in the first 28 days of life that is 20% greater than the growth velocity of premature infants that do not receive protein fortification.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| liquid protein supplement | Experimental | Study subjects will receive standard of care nutrition with the addition of a liquid protein supplement when the baby is able to tolerate an enteral feeding volume of 40mL/kg/day. |
|
| Control group | No Intervention | Study subjects will receive standard of care nutrition |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| liquid protein supplement | Dietary Supplement | The liquid protein supplement is already in use. The purpose of this study is to determine whether using the supplement earlier will lead to improved growth. |
| Measure | Description | Time Frame |
|---|---|---|
| Growth velocity | Growth velocity over the first 28 days of life - Daily weight measurements for the first 28 days of life | up to 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| weight | Extrauterine growth from birth until discharge from the NICU - Weekly weight measurements until discharge from the NICU | average 11 weeks |
| Length | Extrauterine growth from birth until discharge from the NICU - Weekly length measurements until discharge from the NICU |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andrea Weintraub, MD | Icahn School of Medicine at Mount Sinai | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | United States |
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|
| average 11 weeks |
| head circumference | Extrauterine growth from birth until discharge from the NICU - Weekly head circumference measurements until discharge from the NICU | average 11 weeks |