The purpose of this observational study is to investigate the preoperative and operative factor of pain and functional outcome at one years following total knee arthroplasty and spinal surgeon.

Inclusion Criteria:

1. The patients have been waiting for surgery for treatment of osteoarthritis or disc degeneration disease.
2. Must be between 18 and 65 years of age, of either sex.
3. Must demonstrate willingness to participate in the study by signing the written informed consent.

Exclusion Criteria:

1. Patients with Mandatory spondylitis, infections, neoplasms, inflammation, deformities, or previous surgery of spine or knee.
2. The patient is participating in an interventional clinical trial or has in an interventional clinical trial within 30 days prior to enrollment.

Inpatients; Patients have been diagnosed with osteoarthritis or disc degeneration disease.