The purpose of this study is to determine 2% chlorhexidine wipes are effective in preventing of colonization of multi-drug resistant bacteria in intensive care unit patients.

The purpose of this study is to evaluate the usefulness of bathing with chlorhexidine wipe to reduce the risks of multidrug resistant bacteria acquisition and hospital-acquired bloodstream infection among ICU patients

Inclusion Criteria:

• Age > 18 years
• Admission in critical care unit eg. ICU, respiratory care unit, Cardiac care unit with in 24 hours
• Expected duration of critical care unit admission > 48 hours

Exclusion Criteria:

• History of chlorhexidine allergy