Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| S55868 | Other Identifier | UZLeuven |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The analysis of the long-term outcomes and quality-of-life parameters after urethral reconstruction surgery.
Urethroplasty is the surgical repair of a urethral stricture. Depending on the location, severity and length of the stricture, various techniques can be performed.
The first procedure consists of the excision of the stenotic segment and end-to-end anastomosis. Other procedures consist of widening the urethra with buccal mucosa as free graft or with vascularized (genital) skin flaps. The results of these techniques have been described in prospective cohort studies, but to date there is little good data about the functional outcome and quality-of-life with longer follow-up after this surgery.
The purpose of this study is to prospectively follow patients for functional outcome parameters and quality-of-life to obtain long-term information concerning these surgeries.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Urethral stricture | patients requiring surgery for urethral stricture |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| end-to-end urethroplasty | Procedure |
| ||
| substitution urethroplasty (buccal mucosa) |
| Measure | Description | Time Frame |
|---|---|---|
| Quality Of Life: change from baseline (=preoperative value) | Validated questionnaires (patient reported outcome measures) concerning general discomfort, micturition problems, erections, and the impact of those problems on their social life.
| 6m, 1y, 2y, 3y, 4y |
| Measure | Description | Time Frame |
|---|---|---|
| Functional outcomes: micturition: change from baseline (=preoperative value) | Validated questionnaires
| 6m, 1y, 2y, 3y, 4y |
| Functional outcomes: erection: change from baseline (=preoperative value) |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
All patients who underwent urethral reconstruction in our center from 2009 to this date
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Frank Van der Aa, MD-PhD | UZ Leuven | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UZ Leuven | Leuven | Belgium |
Not provided
| ID | Term |
|---|---|
| D014525 | Urethral Stricture |
| ID | Term |
|---|---|
| D014524 | Urethral Obstruction |
| D014522 | Urethral Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
| Procedure |
|
| substitution urethroplasty (pedicled skin flap) | Procedure |
|
Validated questionnaires * International Index of Erectile Dysfunction (IIEF) |
| 6m, 1y, 2y, 3y, 4y |
| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |