PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Healthy Volunteers.

PhotoDynamic Therapy for Line Infection Prevention (PLIP): Pilot Study on Normal Volunteers

We are evaluating the effect of methylene blue and visible light activation on the microbiome of the skin.

Antiseptics are routinely utilized to prevent infections of vascular catheters. We are evaluating the addition of methylene blue and light activation on skin to determine whether this inexpensive and non-toxic treatment can decrease skin pathogens and prevent blood stream infections of long-term vascular catheters. This is a pilot study of normal volunteers to determine the effect on the microbiome of the addition of methylene blue and light activation on antiseptic-treated skin.

Inclusion Criteria:

• Normal individuals without skin problems

Exclusion Criteria:

• Smokers
• Diabetics
• Atopic dermatitis
• G-6-PD deficiency
• Eczema
• Other skin conditions
• Allergies to methylene blue or chlorhexadine