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| ID | Type | Description | Link |
|---|---|---|---|
| I3O-EW-JSBC | Other Identifier | Eli Lilly and Company |
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This type of study is called a radiolabeled study. For this study, LY2801653 (study drug) has been specially prepared to contain radiolabeled carbon [^14C]. [^14C] is a naturally occurring radioactive form of the element, carbon. This study will increase understanding about how the drug appears in the blood, urine, and stool after it is administered to healthy people. Information about any side effects that may occur will also be collected. This study will last up to 15 days for each participant, not including screening. Screening is required within 28 days prior to enrollment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| [^14C]-LY2801653 | Experimental | Single oral dose of LY2801653 containing 100 micro curies of radioactivity |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| [^14C]-LY2801653 | Drug | Administered orally |
|
| Measure | Description | Time Frame |
|---|---|---|
| Urinary and Fecal Excretion of LY2801653 Radioactivity over Time expressed as a Percentage of the Total Radioactive Dose Administered | Pre-dose up to 14 days post dose |
| Measure | Description | Time Frame |
|---|---|---|
| Plasma Pharmacokinetics of LY2801653 and Radioactivity Maximum Observed Concentration (Cmax) | Pre-dose up to 14 days post dose | |
| Plasma Pharmacokinetics of LY2801653 and Radioactivity Time of Maximum Concentration (tmax) | Pre-dose up to 14 days post dose |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST) | Eli Lilly and Company | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. | Madison | Wisconsin |
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| Plasma Pharmacokinetics of LY2801653 and Radioactivity Area Under The Concentration-time Curve from zero to the last timepoint with a measurable Concentration (AUC 0 to tlast) | Pre-dose up to 14 days post dose |
| Relative Abundance of LY2801653 and the Metabolites of LY2801653 in Urine and Feces | Pre-dose up to 14 days post dose |
| Relative Abundance of LY2801653 and the Metabolites of LY2801653 in Plasma | Pre-dose up to 14 days post dose |
| United States |