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| ID | Type | Description | Link |
|---|---|---|---|
| 245.553C | Other Identifier | COEP |
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Hypoactive Sexual Desire Disorder ( HSDD ) is very common in postmenopausal women due to a reduction in circulating androgen levels. The aim of this study is to evaluate the effects of Tribulus Terrestris in premenopausal women with HSDD.
Hypoactive Sexual Desire Disorder ( HSDD ) is the most prevalent female sexual dysfunction in society mainly in postmenopausal women, and is strongly linked to the quality of life of women . The androgen hormones decline over age in the premenopausal period, more sharply after menopause. Tribulus terrestris is a plant native to India , recommended in the treatment of infertility , low libido and impotence . Its main active ingredient is the protodioscin , which has been attributed to an increase in testosterone levels and improved sexual function . The aim of this study is to evaluate the effects of Tribulus Terrestris in premenopausal women with HSDD .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Tribulus Terrestris | Experimental | patients will use Tribulus terrestris (750 mg/day) during 120 days |
|
| Placebo | Placebo Comparator | patients will use placebo for 120 days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tribulus Terrestris | Drug | patients will use 750 mg/day during 120 days |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sexual Desire | we will use the "Quotient Sexual - Version Feminine (QS-F) brazilian questionary to make the evaluation | 120 days |
| Measure | Description | Time Frame |
|---|---|---|
| serum levels of prolactin and thyroid-stimulating hormone (TSH) | Blood test | 120 days |
| Measure | Description | Time Frame |
|---|---|---|
| serum levels of testosterone and sex hormone-binding globulin (SHBG) | Blood test | 120 days |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Selmo Geber, MD PhD | Federal University of Minas Gerais | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital das Clinicas - Universidade Federal de Minas Gerais | Belo Horizonte | Minas Gerais | 30130100 | Brazil |
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| ID | Term |
|---|---|
| D012746 | Sexual Abstinence |
| D057185 | Sedentary Behavior |
| D012735 | Sexual Dysfunction, Physiological |
| ID | Term |
|---|---|
| D012725 | Sexual Behavior |
| D001519 | Behavior |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| C000713868 | Tribulus extract |
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| Placebo | Other | patients will use placebo pills with the same shape of the drug |
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