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To meet eligibility criteria, this study and informed consent of the syndrome of fever associated with bleeding of infectious diseases, severe patients to carry out multicenter, practical randomized controlled clinical research, to compare the curative effect of western medicine, combining Chinese and western medicine treatment, and security, and pathogenesis of TCM and syndrome, severe immune related factor and syndrome type of traditional Chinese medicine, Chinese medicine prescriptions mechanism research.
Randomized method: using large sample, central randomized, parallel comparison of Chinese and western medicine and western medicine group.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TCM and Western Medicine | Experimental | TCM and Western Medicine:First Infectious diseases soup recipe,every time a dose,Two times a day;Ribavirin 10-15mg per kg every time Western Medicine:Ribavirin 10-15mg per kg every time |
|
| Western Medicine | Placebo Comparator | Western Medicine:Ribavirin 10-15mg per kg every time |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Western Medicine | Drug | Physical cooling,Hydrocortisone |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | Anytime of the clinical trail from 2011.1.1 to 2015.12.30 |
| Measure | Description | Time Frame |
|---|---|---|
| Safety outcome | With adverse events as the calculation basis | From 2012.1 to 2015.12 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tan X Hua | Contact | 13500039656 | Gz8htxh@126.com |
| Name | Affiliation | Role |
|---|---|---|
| Tan X Hua | Guangzhou 8th hospitol | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xi 'an eighth people's hospital | Recruiting | XiAn | Shanxi | 710000 | China |
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| ID | Term |
|---|---|
| D006482 | Hemorrhagic Fevers, Viral |
| D003715 | Dengue |
| ID | Term |
|---|---|
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D007239 | Infections |
| D000096724 | Mosquito-Borne Diseases |
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| ID | Term |
|---|---|
| D012254 | Ribavirin |
| ID | Term |
|---|---|
| D012263 | Ribonucleosides |
| D009705 | Nucleosides |
| D009706 | Nucleic Acids, Nucleotides, and Nucleosides |
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| TCM and Western Medicine | Drug | Third Infectious diseases soup recipe |
|
|
| D000079426 |
| Vector Borne Diseases |
| D001102 | Arbovirus Infections |
| D018177 | Flavivirus Infections |
| D018178 | Flaviviridae Infections |