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| Name | Class |
|---|---|
| Canadian International Development Agency | OTHER_GOV |
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The goal of the ACCLAIM (Advancing Community-Level Action for Improving MCH/PMTCT) project is to increase community demand for, uptake of, and retention in Maternal and Child Health (MCH) and/Prevention of Mother-to-child transmission of HIV (PMTCT) services to improve country progress toward elimination of pediatric HIV/AIDS.
This study will undertake a three-arm randomized trial in Swaziland, Uganda and Zimbabwe. Districts/regions (n=9) with 45 PMTCT-implementing health facilities and their catchment areas (populations 7300-27500), will be randomly allocated to three intervention arms: 1) community leader engagement, 2) community leader engagement with community days, or 3) community leader engagement with community days and male and female community peer groups. The primary study outcome is HIV exposed infants (HEI) returning to the health facility within two months for early infant diagnosis (EID) of HIV. Secondary study outcomes include: gestational age of women attending for first antenatal care, male partners tested for HIV, and HEI receiving nevirapine prophylaxis at birth. Changes in community knowledge, attitudes, practices and beliefs on MCH/PMTCT will be assessed through household surveys.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Community Leader Engagement | Other | Trained formal and informal community leaders conducting community dialogues and advocacy, and developing community action plans |
|
| Community Days | Other | Community gatherings involving participatory dialogue, guided discussion, and the provision of education and selected health services. |
|
| Community Peer Groups | Other | Pregnant women attend 4 weekly peer-led classes in community peer groups. Men attending 4 peer-led education sessions in community peer groups |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Community leader engagement | Behavioral | Community leaders conducting advocacy, community dialogue and community action plans on PMTCT/MCH |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of HIV-exposed infants returning to health facility HIV testing | The general objective for the study is to assess the efficacy of the three study arm activities on the uptake of, and retention of HIV positive pregnant/postpartum women in MCH/PMTCT services as measured by the proportion of infants returning to the health facility at 6-8 weeks of age for the early infant diagnosis (EID) of HIV. | 6-8 weeks after birth |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Godfrey Woelk, PhD | Elizabeth Glaser Pediatric AIDS Foundation | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Elizabeth Glaser Pediatric AIDS Foundation | Mbabane | Eswatini | ||||
| Elizabeth Glaser Pediatric AIDS Foundation |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26883307 | Derived | Woelk GB, Kieffer MP, Walker D, Mpofu D, Machekano R; Project ACCLAIM Study Group. Evaluating the effectiveness of selected community-level interventions on key maternal, child health, and prevention of mother-to-child transmission of HIV outcomes in three countries (the ACCLAIM Project): a study protocol for a randomized controlled trial. Trials. 2016 Feb 16;17:88. doi: 10.1186/s13063-016-1202-y. |
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The dataset may be available in 2018. Enquiries may be made with the organization.
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| ID | Term |
|---|---|
| D000163 | Acquired Immunodeficiency Syndrome |
| ID | Term |
|---|---|
| D015658 | HIV Infections |
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
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| Community days | Behavioral | The provision of facilitated dialogues, advocacy and education, and selected health services, to a community on a specific day |
|
| Community Peer Groups | Behavioral | Pregnant women in community peer groups receiving information and education on PMTCT/MCH through 4 weekly peer-led classes . Men in community peer groups receiving information and education on their role in supporting women and families through 4 peer-led education sessions. |
|
| Kampala |
| Uganda |
| Elizabeth Glaser Pediatric AIDS Foundation | Harare | Zimbabwe |
| D015229 |
| Sexually Transmitted Diseases, Viral |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012897 | Slow Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |