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The purpose of this study is evaluate the efficacy of perioperative continuous lumbar plexus block in reducing the risk of cardiac ischemic events of elderly patients undergoing surgery for hip fractures, expressed as a reduction of ischemic events per subject.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intravenous patient-controlled analgesia | Active Comparator | Intravenous morphine solution 0.2 mg / ml in PCA mode without basal infusion, 1mg bolus demand and lockout of 8 minutes. |
|
| Continuous lumbar plexus (LP) block analgesia | Experimental | Continuous lumbar plexus (LP) block analgesia. Continuous infusion of a solution of 0.1% bupivacaine in PCA mode, programmed at 8 ml / h. Rescue bolus 5 ml and 30 minutes lockout |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Continuous lumbar plexus (LP) block analgesia | Procedure |
| ||
| Intravenous patient-controlled analgesia |
| Measure | Description | Time Frame |
|---|---|---|
| evaluate the efficacy of perioperative continuous lumbar plexus block in reducing the risk of cardiac ischemic events of elderly patients undergoing surgery for hip fractures, expressed as a reduction of ischemic events per subject. | 3 days |
| Measure | Description | Time Frame |
|---|---|---|
| Major cardiovascular events (myocardial infarction, acute pulmonary edema, arrhythmias). | 3 days | |
| hospital death | 3 days | |
| Death at 30, 90 and 360 days after surgery |
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Inclusion Criteria:
Previous myocardial infarction Chronic stable angina Atypical angina with positive exercise test for coronary flow failure. Evidence of coronary artery disease with ultrasound, scintigraphic or angiographic compatible
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Division de Anestesia - Pontificia Universidad Catolica de Chile | Santiago | Santiago Metropolitan | 8330024 | Chile | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33238043 | Derived | Guay J, Kopp S. Peripheral nerve blocks for hip fractures in adults. Cochrane Database Syst Rev. 2020 Nov 25;11(11):CD001159. doi: 10.1002/14651858.CD001159.pub3. |
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| Drug |
|
| 1 year |
| Perioperative Pain Intensity, measured in numerical rating scale (NRS). | 3 days |
| Evaluate Adverse events (hypotension, respiratory depression, systemic toxicity, etc..) | 3 days |
| División de Anestesia - Facultad de Medicina Pontificia Universidad Católica |
| Santiago |
| Santiago Metropolitan |
| 8330024 |
| Chile |
| ID | Term |
|---|---|
| D006620 | Hip Fractures |
| ID | Term |
|---|---|
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D025981 | Hip Injuries |
| D007869 | Leg Injuries |
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| ID | Term |
|---|---|
| D016058 | Analgesia, Patient-Controlled |
| ID | Term |
|---|---|
| D000698 | Analgesia |
| D000760 | Anesthesia and Analgesia |
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