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Postoperative ileus is a common after abdominal surgery. Multifactorial etiology such as surgical trauma, bowel manipulation and perioperative opioids contributes to delayed return of normal gut function Chewing gum has recently been used as a form of sham feeding to stimulate acceleration of gut function after abdominal surgery.
The investigators hypothesize that sham feeding with chewing gum will accelerate return of gut function after liver transplantation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| gum chewing | Experimental | Gum type was standardized with all subjects receiving sugar-free xylitol gum. The patients in the chewing gum group, gum chewing began the morning of postoperative day 1. Patients chewed gum (two tablets) 3 times daily in the morning, afternoon, and evening for 15 min. The administration of the therapy was implemented by ICU nurses and recorded in the clinical report form file. All gum-chewing patients completed their course of gum chewing until gas out. |
|
| Control | Placebo Comparator | Routine care during NPO |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| gum chewing | Other | gum chewing |
| |
| Control |
| Measure | Description | Time Frame |
|---|---|---|
| time to flatus | an expected average of 75 hours |
| Measure | Description | Time Frame |
|---|---|---|
| percentage of target calories | an average 4 days | |
| ICU length of stay | an average 96 hous | |
| hospital length of stay |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hogeol Ryu, MD. PhD. | Seoul National University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Seoul | 110-744 | South Korea |
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| ID | Term |
|---|---|
| D002638 | Chewing Gum |
| ID | Term |
|---|---|
| D053149 | Plant Gums |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
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| Other |
Routine care during NPO |
|
| an average 20 days |
| D011134 |
| Polysaccharides |
| D002241 | Carbohydrates |
| D053147 | Plant Exudates |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D002182 | Candy |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |