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| Name | Class |
|---|---|
| National Pecan Shellers Association | UNKNOWN |
The objective of this randomized, controlled feeding study is to investigate the potential health benefits of a pecan-containing diet. The investigators hypothesize the chronic consumption of pecans will improve an array of biomarkers related to cardiovascular disease and type 2 diabetes risk, including indices of oxidative stress, antioxidant activity, inflammation, endothelial function, and insulin resistance when compared with a control diet that is absent nuts.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pecan-containing diet | Active Comparator | Test diet containing 1.5 oz pecans/2000 kcal/day for 28 days |
|
| Nut-free diet | Placebo Comparator | Placebo diet containing no nuts or nut products, and identical in total fat and fiber as the test diet, for 28 days |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pecan-containing diet | Other |
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in biomarkers of oxidative stress compared with control diet | Baseline and 4 weeks | |
| Change in biomarkers of inflammation compared with control diet | Baseline and 4 weeks. | |
| Change in biomarkers of endothelial function compared with control diet | Baseline and 4 weeks. | |
| Change in biomarkers of antioxidant activity compared with control diet | Baseline and 4 weeks | |
| Change in biomarkers of insulin resistance compared with control diet | Baseline and 4 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change in blood pressure compared with control diet | Baseline and 4 weeks | |
| Change in plasma lipid profile compared with control diet | Baseline and 4 weeks. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University | Boston | Massachusetts | 02111 | United States |
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| ID | Term |
|---|---|
| D004043 | Dietary Fiber |
| ID | Term |
|---|---|
| D004040 | Dietary Carbohydrates |
| D002241 | Carbohydrates |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
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| Nut-free diet | Other |
|
|
| D010829 |
| Physiological Phenomena |
| D019602 | Food and Beverages |