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Collect information about WILLFACT or WILFACTIN in their real life clinical use and identify the therapeutic practices in an international environment.
Non-interventional, prospective, non comparative, international, multicentre study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Von Willebrand factor deficient patient | Inherited von Willebrand disease |
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| Measure | Description | Time Frame |
|---|---|---|
| Documentation of product consumption data | Product consumption (VWF International Units) by analysis of posology, frequency in relation to the severity of bleeding, type of surgery and other clinical situations. | at each follow-up visit, up to 24 months |
| Measure | Description | Time Frame |
|---|---|---|
| Collection and analysis of adverse events and VWF immunological safety | Adverse event (type, seriousness, severity, frequency, outcome), anti VWF-antibody and anti FVIII-antibody. | at each follow-up visit, up to 24 months |
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Inclusion Criteria:
Exclusion Criteria:
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Any patient, whatever their age, with inherited von Willebrand disease
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| Name | Affiliation | Role |
|---|---|---|
| Wolfgang MIESBACH, Dr | Medizinische Klinik III, Goethe Universitat, D-60590 Frankfurt/Main (Germany) | Study Director |
| Flora PEYVANDI, Prof. | Faculty of Medicine, University of Milan, 20122 Milan (Italy) | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hopital des enfants Reine Fabiola | Antwerp | Belgium | ||||
| UZA hopital universitaire |
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| ID | Term |
|---|---|
| D014842 | von Willebrand Diseases |
| ID | Term |
|---|---|
| D025861 | Blood Coagulation Disorders, Inherited |
| D001778 | Blood Coagulation Disorders |
| D006402 | Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
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| Edegem |
| 2650 |
| Belgium |
| University Hospital | Brno | 625 00 | Czechia |
| University Central Hospital | Helsinki | Finland |
| Charité Universitätsmedizin | Berlin | Germany |
| GZRR Gerinnungszentrum Rhein/ Ruhr | Duisburg | Germany |
| Universitatsklinikum | Essen | Germany |
| Goethe Universitat | Frankfurt | 60590 | Germany |
| Medizinische Hochschule Hannover | Hanover | Germany |
| Werlhof-Institut für Hämostaseologie GmbH | Hanover | Germany |
| Universitätsklinikum Schleswig-Holstein | Kiel | Germany |
| Universitatsklinikum | Mainz | Germany |
| Klinikum der Universität | München | Germany |
| Hemophilia center "LAIKO" general hospital | Athens | Greece |
| Centro di Riferimento Regionale per Emofilia e Trombosi | Catania | Italy |
| AOUC- Azienda Ospedaliero-Universitaria Carregi | Florence | Italy |
| University of Milan | Milan | 20122 | Italy |
| Oslo University Hospital | Oslo | Norway |
| D020147 | Coagulation Protein Disorders |
| D001791 | Blood Platelet Disorders |
| D006474 | Hemorrhagic Disorders |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |