Clinic Trial in Phase 1 Using Amniotic Membrane for the Skin Replacement in Big Wounds

Clinic Trial in Phase 1 Using Amniotic Membrane for the Skin Replacement in Big Wounds

The purpose of this study is to determine the safety of use of a new therapeutic strategy for the treatment of patients with large wounds

Amniotic membrane (AM) is a useful tissue as a biological dressing with numerous advantages it has a very similar structure to the skin and his biological and immunological properties.

Inclusion Criteria:

• Acute wounds in granulation phase with a minimum surface of 100cm2
• ≥ 18 years
• signing informed consent form
• guarantee adherence to protocol

Exclusion Criteria:

• chronic arterial insufficiency
• pregnant patients, lactating women or fertile adults that they don't use an effective contraceptive method
• involved in other assay
• previous disease; kidney, heart, hepatic, systemic or immune
• inability to understand informed consent form