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| Name | Class |
|---|---|
| St. Olavs Hospital | OTHER |
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The intention of this study is to determine whether the precision of the measure of cardiac output can be optimized by conducting the measurement while the participant is instructed to exhale slowly. This will be compared to measurements done at random to respiration and timed with the participant's spontaneous expiration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| random to respiration | Active Comparator | Cardiac output measurement at random to respiration |
|
| timed with expiration start | Experimental | Cardiac output measurement synchronised at start of expiration. |
|
| timed to instructed exhalation | Experimental | Cardiac output measurement timed to instructed exhalation. The patient will receive instructions to exhale slowly using a peak expiratory flow (PEF)-flute and the cardiac output measurement will be started (i.e bolus given) at the start of expiration. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiac output measurement at random to respiration | Procedure | Cardiac output measurement obtained by pulmonary artery catheter thermodilution technique (PAC TD) |
|
| Measure | Description | Time Frame |
|---|---|---|
| The observed variance amongst the cardiac output measures | The measures will be obtained the first postoperative morning by pulmonary artery catheter thermodilution technique. In total 24 measurements will be done in each patient, i.e 8 measurements in each interventional series described later. The variance observed will create the foundation for calculating the precision of the measures. | 1 hour |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Idar Kirkeby-Garstad, Dr. | Norwegian University of Science and Technology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of circulation and medical imaging, NTNU | Trondheim | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26497869 | Result | Kjetsa E, Skjaervold NK, Skogvoll E, Kirkeby-Garstad I. Synchronizing thermodilution cardiac output measurements with spontaneous breathing does not improve precision. Acta Anaesthesiol Scand. 2016 Mar;60(3):354-9. doi: 10.1111/aas.12650. Epub 2015 Oct 26. |
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| Cardiac output measurement synchronised at start of expiration | Procedure | Cardiac output measurement obtained by PAC TD |
|
| Cardiac output measurement timed to instructed exhalation | Procedure | Cardiac output measurement obtained by PAC TD |
|
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
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