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The purpose of this study is to determine findings of positron emission tomography and diffusion weighted magnetic resonance in primary lesion and axillary metastasis of breast cancer and compare of two imaging modality in these patients.
We aimed that to correlate both primary lesion 18F-fluorodeoxyglucose (FDG) maximum standardized uptake value (SUVmax) and diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) with clinicopathological prognostic factors and compare the prognostic value of these indexes in breast cancer in this study. The evaluated and compared parameters are SUVmax and ADC according to age, tumour size, lymph node metastasis, receptor status, histologic grade, modified Nottingham prognostic index.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Histologic grade | According to the modified criteria of Bloom and Richardson grading system: grade 1, 2 and 3 | ||
| Axillary metastasis | Group A: axillary lymph node metastasis Group B: no axillary lymphatic metastasis | ||
| Modified Nottingham prognostic index | NPI = pathological tumour size (cm) × 0.2 + lymph node stage (1, 2 or 3) + histological grade (1, 2 or 3) The cut-off points of the index were 3.4 and 5.4 to divide patients into the good (≤3.4), moderate (3.41-5.4) and poor (>5.4) prognostic groups | ||
| Oestrogen receptor status | Negative Positive | ||
| Progesterone receptor status | Negative Positive | ||
| HER-2 neu status | Negative Positive |
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| Measure | Description | Time Frame |
|---|---|---|
| To evaluate the relationships between both SUVmax and ADC and clinicopathological prognostic factors | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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Female patients with breast cancer
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| Name | Affiliation | Role |
|---|---|---|
| AYNUR OZEN, MD | Bagcilar Training & Research Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bagcilar Training and Research Hospital | Istanbul | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| D017437 |
| Skin and Connective Tissue Diseases |