Prospective Evaluation of Anorganic Bovine Bone Mineral Versus Calcium Phosphosilicate Alloplastic Bone Putty in Direct Sinus Augmentation: a Spilt-mouth Study

Prospective Evaluation of Anorganic Bovine Bone Mineral Versus Calcium Phosphosilicate Alloplastic Bone Putty in Direct Sinus Augmentation: a Spilt-mouth Study

The purpose of this split-mouth clinical study is to evaluate the clinical, radiographic and histological outcomes of lateral window sinus augmentation with a bovine xenograft or a CPS putty bone substitute in posterior maxillary sites and the survival of implants placed in these sites following healing.

Inclusion Criteria:

• Adult patients with non-contributory medical history that will present for bilateral sinus lift surgery prior to implant placement

Exclusion Criteria:

• Patients that will not agree to participate in this study or sign the consent form
• More than 8mm of residual bone height at the implant site
• Subjects smoking more than 10 cigarettes per day
• History of acute sinus infection
• History of prior maxillary sinus surgery (Caldwell-Luc, direct or indirect sinus lift, etc)
• Medications that affect bone healing (chronic steroid regimen, oral or IV bisphosphonates, etc.)
• Patients allergic to bovine derivatives
• Patients who are a carrier of transmissible disease(s) that may unnecessarily expose laboratory personnel to risks
• Females during pregnancy or lactation or females that plan to become pregnant in the following year (pregnancy test prior to enrollment)