Transcutaneous pO2, Transcutaneous pCO2 and Central Venous SO2 Variations to Define Fluid Responsiveness

Fluid challenge is often carried out in critical ill patients. Its responsiveness usually requires invasive monitoring. To use non-invasive methods is very tempting. Investigators hypothesize that transcutaneous pO2,transcutaneous pCO2 and Central Venous SO2 variations provide feasible estimation on fluid responsiveness in critical ill patients.

Inclusion Criteria:

• 18 years and older ICU patients;
• Septic shock;
• Monitored with PICCO or Swan-Ganz catheter;
• The decision of fluid challenge made by the treating physician;

Exclusion Criteria:

• Evidence of fluid overload;
• Pregnancy